US4488969A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fibrous media containing millimicron-sized particulates
Assignee: Specialty Materials Inc
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Filing: 1983-12-06
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Granted: 1984-12-18
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Expires: 2003-12-06
Abstract
Abstract A self-supporting fibrous matrix containing immobilized therein at least about 5% by weight of microparticulate, with an average diameter less than 1 micron, preferably fumed silica, or alumina, and flocculating amounts of an organic polycationic resin and an organic polyanionic resin, is useful for fluid treatment and filtration processes, especially delipidization and depyrogenation of fluids such as serum.
Inventors
- 👤 Kenneth C. Hou
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 04:20
CPC Classifications
B; B01; B01J; B01J20/00; B01J20/28; B01J20/28002; B01J20/28004; A; A61; A61K; A61K35/00; A61K35/12; A61K35/14; A61K35/16; A61L; A61L2/00; A61L2/02; A61L2/022; B01D; B01D39/00; B01D39/14; B01J20/28014; B01J20/28028; B01J20/28033; B01J20/28052; A61L2103/00; A61L2103/05
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
66 words
A process of delipidizing a lipid-containing fluid which comprises contacting said fluid with a self supporting fibrous matrix containing immobilized therein at least about 5% by weight of a microparticulate material having an average diameter of less than 1 micron, an organic polycationic resin and an organic polyanionic resin, wherein said resins are present in an amount effective to flocculate said microparticulate material in said matrix.
Claim 2
Dependent Claim
66 words
A process of delipidizing a lipid-containing fluid which comprises contacting said fluid with a self supporting fibrous matrix containing immobilized therein at least about 5% by weight of a microparticulate material having an average diameter of less than 1 micron, an organic polycationic resin and an organic polyanionic resin, wherein said resins are present in an amount effective to flocculate said microparticulate material in said matrix.
Claim 3
Dependent Claim
24 words
The process of claim 1 wherein said matrix is in the form of a sheet and said lipid-containing fluid is flowed through said sheet.
Claim 4
Dependent Claim
17 words
The process of claim 1 wherein said lipids in said fluid comprise Hepatitis B Surface Antigen (HBsAg).
Claim 5
Dependent Claim
11 words
The process of claim 1, wherein the microparticulate is fumed silica.
Claim 6
Dependent Claim
19 words
The process of claim 4, wherein the fumed silica has an average particle diameter of 5 to 20 millimicrons.
Claim 7
Dependent Claim
22 words
The process of claim 5, wherein the matrix further comprises a coarse siliceous particulate having an average diameter greater than 1 micron.
Claim 8
Dependent Claim
29 words
The process of claim 6, wherein the matrix contains 5-95 parts of fumed silica to 95-5 parts of coarser siliceous particulate per 100 parts by weight of total particulate.
Claim 9
Dependent Claim
12 words
The process of claim 1, wherein the microparticulate material is fumed alumina.
Claim 10
Dependent Claim
15 words
The process of claim 8, wherein the matrix is in the form of a sheet.
Claim 11
Dependent Claim
43 words
The process of claim 8, wherein the matrix comprises one fibrous component which is unrefined cellulose pulp having a CSF of +400 to +800 ml; and another fibrous component which is highly refined cellulose pulp having a CSF of +100 to -600 ml.
Claim 12
Dependent Claim
19 words
The process of claim 10, wherein the ratio of unrefined to refined pulp is about 2:1 to about 10:1.
Claim 13
Dependent Claim
66 words
A process for depyrogenating a pyrogen-containing fluid which comprises contacting said fluid with a self supporting fibrous matrix containing immobilized therein at least about 5% by weight of a microparticulate material having an average diameter of less than 1 micron, an organic polycationic resin and an organic polyanionic resin, wherein said resins are present in an amount effective to flocculate said microparticulate material in said matrix.
Claim 14
Dependent Claim
66 words
A process for depyrogenating a pyrogen-containing fluid which comprises contacting said fluid with a self supporting fibrous matrix containing immobilized therein at least about 5% by weight of a microparticulate material having an average diameter of less than 1 micron, an organic polycationic resin and an organic polyanionic resin, wherein said resins are present in an amount effective to flocculate said microparticulate material in said matrix.
Claim 15
Dependent Claim
25 words
The process of claim 12 wherein said matrix is in the form of a sheet and said pyrogen containing fluid is flowed through said sheet.
Claim 16
Dependent Claim
12 words
The process of claim 12 wherein the microparticulate material is fumed silica.
Claim 17
Dependent Claim
11 words
The process of claim 12, wherein the microparticulate is fumed alumina.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-18 | 1988-06-18 | 1988-12-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-18 | 1992-06-18 | 1992-12-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-18 | 1996-06-18 | 1996-12-18 | $7700.00 | Window Closed / Lapsed |