US4485091A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dermatological compositions
Assignee: Quinoderm Ltd
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Filing: 1982-07-12
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Granted: 1984-11-27
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Expires: 2002-07-12
Abstract
Abstract A dermatological composition in the form of a cream, lotion or gel contains hydrogen peroxide. The composition has an oil medium dispersed in an aqueous medium and the hydrogen peroxide is contained in the aqueous medium together with a buffer to maintain an acid pH.
Inventors
- 👤 Harry Fitton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 11:14
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/70; A61K31/715; A61K33/00; A61K33/40; A61K47/00; A61K47/30; A61K47/36
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
127 words
A method of preparing a dermatological composition in the form of a cream preparation, said composition having an oil medium dispersed in an aqueous medium, and incorporating starch gel, said aqueous medium containing hydrogen peroxide and a buffer to maintain the pH of the composition at less than 7, comprising the steps of: i. forming a mixture of that part of said aqueous medium not including said hydrogen peroxide, and said oil medium and starch; ii. stirring and heating said mixture so that said starch is converted to said starch gel in situ thereby forming a stable, smooth oil-in-water emulsion; iii. cooling said emulsion; iv. adding the remainder of said aqueous medium including said hydrogen peroxide to said cooled emulsion and stirring to give a uniform mixture.
Claim 2
Independent Claim
127 words
A method of preparing a dermatological composition in the form of a cream preparation, said composition having an oil medium dispersed in an aqueous medium, and incorporating starch gel, said aqueous medium containing hydrogen peroxide and a buffer to maintain the pH of the composition at less than 7, comprising the steps of: i. forming a mixture of that part of said aqueous medium not including said hydrogen peroxide, and said oil medium and starch; ii. stirring and heating said mixture so that said starch is converted to said starch gel in situ thereby forming a stable, smooth oil-in-water emulsion; iii. cooling said emulsion; iv. adding the remainder of said aqueous medium including said hydrogen peroxide to said cooled emulsion and stirring to give a uniform mixture.
Claim 3
Dependent Claim
16 words
The process of claim 1, wherein the composition contains up to 3.75% by weight hydrogen peroxide.
Claim 4
Dependent Claim
16 words
The process of claim 2, wherein the composition contains 0.75% to 2% by weight hydrogen peroxide.
Claim 5
Dependent Claim
15 words
The process of claim 1, 2, or 3, wherein the pH is 2.5 to 6.5.
Claim 6
Dependent Claim
22 words
The process of claim 1, 2, 3 or 4, wherein the oil medium comprises a saturated hydrocarbon wax and an emulsifying wax.
Claim 7
Dependent Claim
29 words
The process of claim 1, 2, 3, 4 or 5, wherein the buffer comprises lactic acid, citric acid, tartaric acid, maleic acid, or hydroxysuccinic acid with an acid salt.
Claim 8
Dependent Claim
26 words
The process of claim 6, wherein the acid salt is sodium or potassium acid phosphate, sodium or potassium acid citrate, or sodium or potassium acid tartrate.
Claim 9
Dependent Claim
33 words
The process of claim 1, 2, 3, 4, 5, 6 or 7, further comprising one or more of a chelating agent, a pharmaceutically active quinoline derivative, chlorhexidine gluconate, urea, hydrocortisone, or a corticosteroid.
Claim 10
Dependent Claim
19 words
The process of claim 8, wherein said quinoline derivative is potassium 8-hydroxyquinoline sulphate, 8-hydroxyquinoline sulphate, iodochlorhydroxyquinoline, di-iodohydroxyquinoline or di(8-hydroxy-7-iodoquinoline-5-sulphonate).
Claim 11
Dependent Claim
26 words
The process of claim 8 or 9, wherein said chelating agent is ethylenediamine tetra-acetic acid or the disodium, trisodium, dipotassium or tripotassium salts of said acid.
Claim 12
Dependent Claim
18 words
A dermatological composition in the form of a cream preparation prepared by the process according to claim 1.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-11-27 | 1988-05-28 | 1988-11-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-11-27 | 1992-05-28 | 1992-11-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-11-27 | 1996-05-28 | 1996-11-27 | $7700.00 | Window Closed / Lapsed |