US4479938A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Therapeutic composition containing factor VIIa
Assignee: Baxter International Inc
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Filing: 1982-06-14
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Granted: 1984-10-30
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Expires: 2002-06-14
Abstract
Abstract Patients having a clotting factor defect can be successfully treated by the administration of a composition containing effective hemostatic amounts of factor VIIa. Preferably, the factor VIIa is substantially free of factors IXa and Xa. Procedures for preparing the above therapeutic compositions are also described.
Inventors
- 👤 William R. Thomas
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 04:36
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/43; A61K38/46; A61K38/48; A61K38/482; A61K38/4846
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
33 words
A composition for treating patients having deficiencies or inhibitors of blood clotting factors which comprises a sterile composition in which the sole effective, activated hemostatic agent is an effective amount of factor VIIa.
Claim 2
Dependent Claim
33 words
A composition for treating patients having deficiencies or inhibitors of blood clotting factors which comprises a sterile composition in which the sole effective, activated hemostatic agent is an effective amount of factor VIIa.
Claim 3
Dependent Claim
18 words
The composition of claim 1 wherein the composition is free of the activity of factors IXa and Xa.
Claim 4
Dependent Claim
10 words
The composition of claim 1 additionally including a stabilizing protein.
Claim 5
Dependent Claim
9 words
The composition of claim 1 which additionally includes water.
Claim 6
Dependent Claim
18 words
The composition of claim 4 wherein the concentration of factor VII is about from 0.1 to 10.0 ug/ml.
Claim 7
Dependent Claim
33 words
A hermetically-sealed container having a pierceable, flexible cap, a sterile interior and containing therein a sterile, dry composition in which the sole effective, activated hemostatic agent is an effective amount of factor VIIa.
Claim 8
Dependent Claim
33 words
A hermetically-sealed container having a pierceable, flexible cap, a sterile interior and containing therein a sterile, dry composition in which the sole effective, activated hemostatic agent is an effective amount of factor VIIa.
Claim 9
Dependent Claim
25 words
The container of claim 6 wherein the dry composition is reconstituted in water to a concentration of about from 0.1 to 10.0 μg. factor VIIa/ml.
References Cited (Backward Citations)
US3560475A
Cited
US4160025A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-10-30 | 1988-04-30 | 1988-10-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-10-30 | 1992-04-30 | 1992-10-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-10-30 | 1996-04-30 | 1996-10-30 | $7700.00 | Window Closed / Lapsed |