Patent US5031176A successfully refreshed from Google Patents.
US4476017A
Expired / Lapsed
US
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Removable synthesis column
Assignee: Beckman Coulter Inc
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Filing: 1983-06-03
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Granted: 1984-10-09
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Expires: 2003-06-03
Abstract
Abstract A column for use in DNA synthesis. The column is transparent and is disposable to allow access to the resin beads within the column. The column includes end caps which are engageable with a housing and a screw to secure the column in the housing.
Inventors
- 👤 Daniel H. Scharff
- 👤 Lev J. Leytes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 11:31
CPC Classifications
C; C07; C07H; C07H21/00; B; B01; B01J; B01J19/00; B01J19/0046; B01J2219/00; B01J2219/00274; B01J2219/00277; B01J2219/00279; B01J2219/00281; B01J2219/00286; B01J2219/00351; B01J2219/00423; B01J2219/00497; B01J2219/005; B01J2219/00583; B01J2219/0059; B01J2219/00596; B01J2219/00718; B01J2219/0072; B01J2219/00722; C40; C40B; C40B40/00; C40B40/04; C40B40/06; C40B60/00; C40B60/14; G; G01; G01N; G01N30/00; G01N30/02; G01N30/60; G01N30/6004; G01N30/6047; G01N30/6052; G01N30/6082; G01N30/6091
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
121 words
A synthesis column assembly for use in a DNA synthesis instrument, comprising: (a) a tube defining a passage extending the length of said tube, said tube terminating in a first end and a second end; (b) first and second filtering means for filtering a liquid flowing through said tube, each filtering means having one end extending into and being frictionally held by a respective end of the passage; (c) first and second sealing means for sealing the ends of the tube to the DNA synthesis instrument, each sealing means defining an opening for receiving the other end of a respective filtering means; (d) whereby each sealing means is held against the respective end of the tube by the respective filtering means.
Claim 2
Dependent Claim
121 words
A synthesis column assembly for use in a DNA synthesis instrument, comprising: (a) a tube defining a passage extending the length of said tube, said tube terminating in a first end and a second end; (b) first and second filtering means for filtering a liquid flowing through said tube, each filtering means having one end extending into and being frictionally held by a respective end of the passage; (c) first and second sealing means for sealing the ends of the tube to the DNA synthesis instrument, each sealing means defining an opening for receiving the other end of a respective filtering means; (d) whereby each sealing means is held against the respective end of the tube by the respective filtering means.
Claim 3
Dependent Claim
21 words
The assembly of claim 1 in which the passage contains resin beads that are held in place by the filtering means.
Claim 4
Dependent Claim
55 words
The assembly of claim 1 in which the depths of the openings of the sealing means are less than the thicknesses of the sealing means, and in which the sealing means define liquid flow passages that have sizes similar to those of the connecting lines through which the instrument supplies liquid to the column assembly.
Claim 5
Dependent Claim
19 words
The assembly of claim 1 in which the openings of the sealing means extend entirely through the sealing means.
Claim 6
Dependent Claim
25 words
The assembly of claim 4 in which said other ends of the filtering means and the openings of the respective sealing means have matching tapers.
Claim 7
Dependent Claim
25 words
The assembly of claim 4 in which the outer ends of the filtering means are flush with the outer surfaces of the respective sealing means.
Claim 8
Dependent Claim
11 words
The assembly of claim 1 in which the tube is transparent.
Claim 9
Dependent Claim
13 words
The assembly of claim 1 in which the tube is a glass tube.
Claim 10
Dependent Claim
14 words
The assembly of claim 1 in which the tube is a transparent plastic tube.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-10-09 | 1988-04-09 | 1988-10-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-10-09 | 1992-04-09 | 1992-10-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-10-09 | 1996-04-09 | 1996-10-09 | $7700.00 | Window Closed / Lapsed |