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US4468378A Expired / Lapsed US ⏱️ 0.0 years remaining

Oxysulfonic derivative of copolymer of acrolein and acrylic acid and direct action anticoagulant on its basis

Assignee: Individual
•
Filing: 1981-05-29
•
Granted: 1984-08-28
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Expires: 2001-05-29
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Abstract

Abstract According to the invention, the oxysulfonic derivative of the copolymer of acrolein and acrylic acid is of the following formula: ##STR1## where n=190 to 600, m=190 to 500, and p=830 to 850. This biologically active compound can be used as a direct and prolonged action blood antiacoagulant to be administered in the form of 1- or 2-percent solutions. The preparation according to the invention features a long shelf and has a longer action than the well-known heparin.

Inventors

  • 👤 Mikhail G. Voronkov
  • 👤 Ada T. Platonova
  • 👤 Vladislava Z. Annenkova
  • 👤 Valentina M. Annenkova
  • 👤 Valentina B. Kazimirovskaya
  • 👤 Galina S. Ugrjumova

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 08:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74; A61K31/765; A61K31/78; Y; Y10; Y10S; Y10S128/00; Y10S128/22

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 38 words
A direct and prolonged action low toxicity anticoagulant of blood, comprising an active principle which is an oxysulfonate derivative of the copolymer of acrolein and acrylic acid of the formula: and a liquid carrier for said active principle.
Claim 2
Dependent Claim 38 words
A direct and prolonged action low toxicity anticoagulant of blood, comprising an active principle which is an oxysulfonate derivative of the copolymer of acrolein and acrylic acid of the formula: and a liquid carrier for said active principle.
Claim 3
Dependent Claim 21 words
An anticoagulant of blood as claimed in claim 1, wherein the active principle content is 1 to 2 percent by weight.

References Cited (Backward Citations)

US3129195A Cited
EP0010621A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-08-28 1988-02-27 1988-08-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-08-28 1992-02-27 1992-08-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-08-28 1996-02-27 1996-08-28 $7700.00 Window Closed / Lapsed

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