US4465794A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hydrophilic polymers and contact lenses therefrom
Assignee: Allergan Inc
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Filing: 1982-02-04
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Granted: 1984-08-14
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Expires: 2002-02-04
Abstract
Abstract There is prepared a hydrophilic water swellable water insoluble copolymer of (1) at least 35% of a hydroxy (C 2 -C 4 -alkyl)-2-alkenoate, (2) 30 to 60% of a 2-alkenamide or an N,N-di (C 1 -C 6 -alkyl)2-alkenamide, (3) 5 to 20% of R --OR 1 ) x Z where R is C 1 -C 6 alkyl, R 1 is C 2 -C 4 alkylene, x is an integer of 1 to 4 and Z is 2-alkenoyloxy and (4) 0.3 to 5% of a polyethylenically unsaturated crosslinking agent having a relatively long aliphatic chain, the copolymer being capable of holding 80 to 80 weight % of water. The polymers are particularly useful in preparing hydrophilic contact lenses of high burst strength and extended wear properties.
Inventors
- 👤 Petr Kuzma
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 09:32
CPC Classifications
G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; C; C08; C08F; C08F220/00; C08F220/02; C08F220/10; C08F220/20; C08F220/26; C08F220/28; C08F220/281
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
149 words
A hydrophylic contact lens having a water content of 58 to 80 weight % based on the total of water plus dry polymer and made of a hydrophilic water swellable copolymer of at least one monomer from each of the following four subclasses: (1) at least 35% hydroxy (C 2 -C 4 alkyl)2-alkenoate, (2) 30 to 60% of a 2-alkenamide or an N,N-di)C 1 -C 6 alkyl)2-alkenamide, (3) 5 to 20% R--OR 1 ) x Z where R is C 1 -C 6 alkyl, wherein R 1 is C 2 -C 4 alkylene, wherein x is an integer from 1 to 4 and wherein Z is 2-alkenoyloxy, (4) 0.3 to 5% of a polyethylenically unsaturated cross-linking agent having the formula ##STR2## where R 2 and R 3 are hydrogen or lower alkyl, n is an integer of 2 to 4 and y is an integer of 2 to 9.
Claim 2
Dependent Claim
149 words
A hydrophylic contact lens having a water content of 58 to 80 weight % based on the total of water plus dry polymer and made of a hydrophilic water swellable copolymer of at least one monomer from each of the following four subclasses: (1) at least 35% hydroxy (C 2 -C 4 alkyl)2-alkenoate, (2) 30 to 60% of a 2-alkenamide or an N,N-di)C 1 -C 6 alkyl)2-alkenamide, (3) 5 to 20% R--OR 1 ) x Z where R is C 1 -C 6 alkyl, wherein R 1 is C 2 -C 4 alkylene, wherein x is an integer from 1 to 4 and wherein Z is 2-alkenoyloxy, (4) 0.3 to 5% of a polyethylenically unsaturated cross-linking agent having the formula ##STR2## where R 2 and R 3 are hydrogen or lower alkyl, n is an integer of 2 to 4 and y is an integer of 2 to 9.
Claim 3
Dependent Claim
44 words
A contact lens according to claim 1 wherein (1) is a hydroxy (c 2 -C 4 alkyl) acrylate, methacrylate or crotonate, (2) is acrylamide, methacrylamide or crotonamide or N,N-di(C 1 -C 6 alkyl) acrylamide, methacrylamide or crotonamide and Z is acryloyloxy, methacryloyloxy or crotonoyloxy.
Claim 4
Dependent Claim
86 words
A contact lens according to claim 2: wherein (1) is a hydroxy (C 2 -C 4 alkyl) acrylate or methacrylate, wherein (2) is a acrylamide, methacrylamide, or N,N-di(C 1 -C 3 alkyl) acrylamide or methacrylamide, wherein (3) is a compound when R is C 1 -C 4 alkyl, R 1 is C 2 -C 3 alkylene, and z is acryloyloxy or methacryloyloxy, and wherein (4) is a polyalkylene glycol diacrylate or dimethacryltae oligomer containing from 3 to 10 alkylene glycol moieties in the polyalkylene glycol chain.
Claim 5
Dependent Claim
78 words
A contact lens according to claim 3: wherein (1) is hydroxy C 2 -C 3 alkyl acrylate or methacrylate, wherein (2) is acrylamide, methacrylamide, or N,N-di(C 1 -C 4 ) acrylamide or methacrylamide, wherein (3) is a compound when x is 1 or 2, and wherein (4) is a polyalkylene glycol diacrylate or methacrylate having 3 to 4 alkylene glycol moieties in the polyalkylene glycol chain and wherein the polyalkylene glycol moiety is polyethylene glycol or polypropylene glycol.
Claim 6
Dependent Claim
36 words
A contact lens according to claim 4: wherein (2) is a acrylamide, methacrylamide, or N,N-di(C 1 -C 2 alkyl) acrylamide or methacrylamide, and wherein (3) is a compound when R is C 1 -C 2 alkyl.
Claim 7
Dependent Claim
31 words
A contact lens according to claim 5: wherein (1) is hydroxyethyl methacrylate, wherein (2) is C 1 -C 2 alkoxyethyl methacrylate, wherein (3) is triethylene glycol methacrylate or tetraethylene glycol methacrylate.
Claim 8
Dependent Claim
23 words
A contact lens according to claim 6: wherein (2) is N,N-dimethylacrylamide, wherein (3) is ethoxyethyl methacrylate, and wherein (4) is tetraethylene glycol dimethacrylate.
Claim 9
Dependent Claim
14 words
A contact lens according to claim 1 having a refractive index of about 1.43.
Claim 10
Dependent Claim
34 words
A hydrophilic contact lens according to claim 1 having a water content of 60 to 75%, a burst strength of at least 7 psi/0.1 mm of wet center thickness and extractable of below 10%.
Claim 11
Dependent Claim
71 words
A hydrophilic contact lens according to claim 1 characterized by a water content of 60 to 62%, linear expansion of 37 to 38, burst strength of at least 7 psi/0.1 mm of wet center thickness, extractables below about 10%, no visible change on autoclaving, oxygen permeability of at least 24×10 -10 cm 2 /sec cm Hg, light transmission of at least 99% at λ=660 nm, and a refractive index of 1.43.
References Cited (Backward Citations)
US3965063A
Cited
US4267295A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-08-14 | 1988-02-13 | 1988-08-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-08-14 | 1992-02-13 | 1992-08-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-08-14 | 1996-02-13 | 1996-08-14 | $7700.00 | Window Closed / Lapsed |