US4457921A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of reducing dental caries
Assignee: Intercontinental Great Brands LLC
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Filing: 1983-05-09
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Granted: 1984-07-03
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Expires: 2003-05-09
Abstract
Abstract A method for treating teeth to reduce caries is provided wherein the teeth are contacted with a hydrogenated starch hydrolysate, in the presence of a sugar, for example, as contained in a chewing gum composition or toothpaste or powder composition, the hydrogenated starch hydrolysate and sugar being present in an amount sufficient to inhibit growth of Streptococcus mutans in the oral cavity or on the teeth.
Inventors
- 👤 John J. Stroz
- 👤 Donald A. M. Mackay
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 17:35
CPC Classifications
A; A61; A61Q; A61Q11/00; A23; A23L; A23L27/00; A23L27/30; A23L27/33; A23L27/34; A61K; A61K31/00; A61K31/70; A61K31/715; A61K8/00; A61K8/18; A61K8/30; A61K8/60; A61K8/72; A61K8/73; A61K8/732
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
145 words
In a method of essentially blocking cell division and thereby inhibiting the growth of Streptococcus mutans having near optimum growth occurring in an environment of 0.4 to 0.5% of sucrose, with a slight increase in said growth resulting with an increase of the sucrose concentration to up to 2.0%, the improvement comprising, at a sucrose concentration of 0.4% or more, reducing the level of extracellular polysaccharide production from said sucrose by said Streptococcus mutans with a synergistic amount, in the range of from about 0.25:1.0 to about 4.0:1.0 of a sucrose to sugar substitute ratio at a final carbohydrate concentration of up to 2.0%, of hydrogenated starch hydrolysate non-metabolizing carbohydrate sugar substitute which thereby inhibits or prevents the growth of EPS production from said sucrose by said Streptococcus mutans to an extent greater than that achieved merely by replacement of said sucrose by non-metabolized carbohydrate.
Claim 2
Dependent Claim
145 words
In a method of essentially blocking cell division and thereby inhibiting the growth of Streptococcus mutans having near optimum growth occurring in an environment of 0.4 to 0.5% of sucrose, with a slight increase in said growth resulting with an increase of the sucrose concentration to up to 2.0%, the improvement comprising, at a sucrose concentration of 0.4% or more, reducing the level of extracellular polysaccharide production from said sucrose by said Streptococcus mutans with a synergistic amount, in the range of from about 0.25:1.0 to about 4.0:1.0 of a sucrose to sugar substitute ratio at a final carbohydrate concentration of up to 2.0%, of hydrogenated starch hydrolysate non-metabolizing carbohydrate sugar substitute which thereby inhibits or prevents the growth of EPS production from said sucrose by said Streptococcus mutans to an extent greater than that achieved merely by replacement of said sucrose by non-metabolized carbohydrate.
Claim 3
Dependent Claim
16 words
The improvement of claim 1 wherein said ratio of hydrogenated starch hydrolysate to sucrose is 4.0:1.0.
Claim 4
Dependent Claim
32 words
The improvement of claim 1 wherein said hydrogenated starch hydrolysate is prepared by hydrogenating saccharified starch having a dextrose equivalent of 15-75% and containing dextrines until substantially no dextrose and maltose remain.
Claim 5
Dependent Claim
62 words
The improvement of claim 1 wherein said hydrogenated starch hydrolysate comprises from about 72% to about 80% of solids of which from about 4 to about 20% is sorbitol, from about 5 to about 65% is hydrogenated disaccharides, from about 15 to about 75% is tri- to hepta-hydrogenated saccharides, and from about 10 to about 65% is hydrogenated saccharides higher than hepta.
Claim 6
Dependent Claim
55 words
The improvement of claim 1 wherein said solids portion of said hydrogenated starch hydrolysate contains from about 6 to about 10% sorbitol, and from about 25 to about 55% by weight hydrogenated disaccharides, from about 20 to about 40% hydrogenated tri- to hepta-saccharides, and from about 15 to about 30% hydrogenated saccharides higher than hepta.
Claim 7
Dependent Claim
44 words
The improvement of claim 1 wherein said solids portion of said hydrogenated starch hydrolysate contains from about 8 to about 20% sorbitol, and from about 5 to about 15% by weight hydrogenated disaccharides, and from about 20 to about 75% hydrogenated tri- to penta-saccharides.
Claim 8
Dependent Claim
48 words
The improvement of claim 1 wherein said hydrogenated starch hydrolysate comprises from about 5 to about 8% sorbitol, from about 25 to about 58% hydrogenated disaccharides, from about 20 to about 40% hydrogenated tri- to hexa-saccharides and from about 15 to about 30% hydrogenated saccharides higher than hexa.
Claim 9
Dependent Claim
28 words
The improvement of claim 1 wherein said Streptococcus mutans is contacted with the sucrose/hydrogenated starch hydrolysate combination for a time of from about 5 to about 30 minutes.
References Cited (Backward Citations)
US26959A
Cited
CA899143A
Cited
USRE26959E
Cited
US4013775A
Cited
US3556811A
Cited
US4277464A
Cited
US4134999A
Cited
US4277511A
Cited
US4217368A
Cited
US4208431A
Cited
US4279931A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-07-03 | 1988-01-02 | 1988-07-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-07-03 | 1992-01-02 | 1992-07-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-07-03 | 1996-01-02 | 1996-07-03 | $7700.00 | Window Closed / Lapsed |