US4456628A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for film-coating a particulate solid, and emulsions for conducting the process
Assignee: Individual
•
Filing: 1981-01-07
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Granted: 1984-06-26
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Expires: 2001-01-07
Abstract
Abstract A process of coating a particulate medicinal agent; comprising the application to said medicinal agent of a liquid composition containing a water-insoluble film-forming agent, a lipophilic solvent, a hydrophilic solvent and water, said liquid composition comprising an emulsion with at least two phases, wherein the liquid components of the liquid composition are removed after application of said liquid composition to said particulate medicinal agent.
Inventors
- 👤 Kurt H. Bauer
- 👤 Hermann Osterwald
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 15:18
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/2806; A61K9/2833; A61K9/286; A61K9/2866
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
138 words
In the film-coating of a particulate medicinal agent including the steps of applying to said particulate medicinal agent a liquid composition containing a water-insoluble film-forming agent in a solvent therefor and thereafter drying off the liquid constituents of said liquid composition thereby to form a film on said particulate medicinal agent: the improvement wherein said liquid composition is an emulsion including, by weight: (1) about 10-70% lipophilic solvent; (2) about 5-40% hydrophilic solvent; and (3) about 20-70% water; said emulsion comprising two phases, one of said phases containing the major portion of said lipophilic solvent with the water-insoluble film forming agent dissolved therein, and the other of the said phases containing the major portion of said hydrophilic solvent, the liquid components of the liquid composition being removed after application of said liquid composition to said particulate medicinal agent.
Claim 2
Dependent Claim
138 words
In the film-coating of a particulate medicinal agent including the steps of applying to said particulate medicinal agent a liquid composition containing a water-insoluble film-forming agent in a solvent therefor and thereafter drying off the liquid constituents of said liquid composition thereby to form a film on said particulate medicinal agent: the improvement wherein said liquid composition is an emulsion including, by weight: (1) about 10-70% lipophilic solvent; (2) about 5-40% hydrophilic solvent; and (3) about 20-70% water; said emulsion comprising two phases, one of said phases containing the major portion of said lipophilic solvent with the water-insoluble film forming agent dissolved therein, and the other of the said phases containing the major portion of said hydrophilic solvent, the liquid components of the liquid composition being removed after application of said liquid composition to said particulate medicinal agent.
Claim 3
Dependent Claim
39 words
The improvement of claim 1 wherein said hydrophilic solvent is selected from C 1 -C 5 aliphatic alcohols, C 1 -C 6 aliphatic ketones, mono- or diethers of ethylene glycol with C 1 -C 5 alcohols, or mixtures thereof.
Claim 4
Dependent Claim
26 words
The improvement of claims 1 or 2 wherein said lipophilic solvent comprises a C 1 -C 5 alkyl ester of acetic acid or a mixture thereof.
Claim 5
Dependent Claim
20 words
The improvement of claim 3 wherein said water-insoluble film-forming agent is selected from cellulose acetate phthalate, ethylcellulose and hydroxypropylmethylcellulose phthalate.
References Cited (Backward Citations)
US2722528A
Cited
US2843583A
Cited
US3935326A
Cited
US4385078A
Cited
WO1980000659A1
Cited
US4287221A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-06-26 | 1987-12-26 | 1988-06-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-06-26 | 1991-12-26 | 1992-06-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-06-26 | 1995-12-26 | 1996-06-26 | $7700.00 | Window Closed / Lapsed |