US4446325A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,4-Dihydropyridine compounds
Assignee: Maruko Pharmaceutical Co Ltd
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Filing: 1982-10-19
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Granted: 1984-05-01
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Expires: 2002-10-19
Abstract
Abstract 1,4-Dihydropyridine compounds having excellent coronary and vertebral vasodilation, blood pressure depression and anti-hypertensive activities are disclosed. These compounds are low toxic and stable to light, and are very useful for pharmaceutical agents.
Inventors
- 👤 Sachio Ohno
- 👤 Kiyoshi Mizukoshi
- 👤 Osamu Komatsu
- 👤 Kenzi Ichihara
- 👤 Takashi Morishima
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 02:37
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/80; C07D211/84; C07D405/00; C07D405/02; C07D405/12; C07D211/90; C07D317/00; C07D317/08; C07D317/10; C07D317/14; C07D317/18; C07D317/24; C07D409/00; C07D409/02; C07D409/12
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
70 words
A 1,4-dihydropyridine compound represented by the formula ##STR8## wherein R represents a 2- or 3-nitrophenyl group, R 1 represents a straight or branched chain alkyl group having 1 to 4 carbon atom, R 2 represents hydrogen or a methyl group, X represents an oxygen atom, an ethylenedioxy group, a propylenedioxy group, an ethylenedithio group, a propylenedithio group or an ethylene group, and n is an integer of 1 or 2.
Claim 2
Dependent Claim
70 words
A 1,4-dihydropyridine compound represented by the formula ##STR8## wherein R represents a 2- or 3-nitrophenyl group, R 1 represents a straight or branched chain alkyl group having 1 to 4 carbon atom, R 2 represents hydrogen or a methyl group, X represents an oxygen atom, an ethylenedioxy group, a propylenedioxy group, an ethylenedithio group, a propylenedithio group or an ethylene group, and n is an integer of 1 or 2.
Claim 3
Dependent Claim
46 words
A compound as claimed in claim 1, wherein R represents a 2- or 3-nitrophenyl group, R 1 represents a straight or branched chain alkyl group having 1 to 4 carbon atoms, R 2 represents a methyl group, X represents an ethylenedioxy group, and n is 1.
Claim 4
Dependent Claim
46 words
A compound as claimed in claim 1, wherein R represents a 2- or 3-nitrophenyl group, R 1 represents a straight or branched chain alkyl group having 1 to 4 carbon atoms, R 2 represents a methyl group, X represents an oxygen atom, and n is 1.
Claim 5
Dependent Claim
44 words
A compound as claimed in claim 1, wherein R represents a 2- or 3-nitrophenyl group, R 1 represents a straight or branched chain alkyl group having 1 to 4 carbon atoms, R 2 represents hydrogen, X represents an ethylene group and n is 1.
Claim 6
Dependent Claim
32 words
A compound as claimed in claim 2, wherein R represents a 3-nitrophenyl group, R 1 and R 2 each represents a methyl group, X represents an ethylenedioxy group and n is 1.
Claim 7
Dependent Claim
32 words
A compound as claimed in claim 3, wherein R represents a 2-nitrophenyl group, R 1 and R 2 each represents a methyl group, X represents an oxygen atom, and n is 1.
Claim 8
Dependent Claim
32 words
A compound as claimed in claim 4, wherein R represents a 3-nitrophenyl group, R 1 represents a methyl group, R 2 represents hydrogen, X represents an ethylene group and n is 1.
Claim 9
Dependent Claim
32 words
A compound as claimed in claim 4, wherein R represents a 3-nitrophenyl group, R 1 represents an ethyl group, R 2 represents hydrogen, X represents an ethylene group and n is 1.
Claim 10
Dependent Claim
32 words
A compound as claimed in claim 4, wherein R represents a 3-nitrophenyl group, R 1 represents a propyl group, R 2 represents hydrogen, X represents an ethylene group and n is 1.
References Cited (Backward Citations)
US3485847A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-05-01 | 1987-10-31 | 1988-05-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-05-01 | 1991-10-31 | 1992-05-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-05-01 | 1995-10-31 | 1996-05-01 | $7700.00 | Window Closed / Lapsed |