US4444782A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2(4-tert.-Butyl-2,6-dichlorophenyl-imino)imidazolidine and use as an anti-hypertension agent
Assignee: SmithKline Beecham Corp
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Filing: 1982-12-23
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Granted: 1984-04-24
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Expires: 2002-12-23
Abstract
Abstract 2-(4-tert.-Butyl-2,6-dichlorophenylimino)imidazolidine is a anti-hypertensive chemical compound which has unexpected biological properties compared to those of clonidine.
Inventors
- 👤 Robert M. DeMarinis
- 👤 J. Paul Hieble
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 11:56
CPC Classifications
C; C07; C07C; C07C331/00; C07C331/16; C07C331/28; A; A61; A61P; A61P9/00; A61P9/12; C07D; C07D233/00; C07D233/04; C07D233/28; C07D233/44; C07D233/50
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
7 words
2-(4-tert.-Butyl-2,6-dichlorophenylimino)imidazolidine or its pharmaceutically acceptable addition salts.
Claim 2
Dependent Claim
7 words
2-(4-tert.-Butyl-2,6-dichlorophenylimino)imidazolidine or its pharmaceutically acceptable addition salts.
Claim 3
Dependent Claim
10 words
The compound of claim 1 being 2-(4-tert.-butyl-2,6-dichlorophenylimino)imidazolidine as the base.
Claim 4
Dependent Claim
8 words
The compound of claim 1 being 2-(4-tert.-butyl-2,6-dichlorophenylimino)imidazolidine hydrochloride.
Claim 5
Dependent Claim
27 words
A pharmaceutical composition having anti-hypertensive activity comprising a nontoxic, anti-hypertensively effective quantity of a compound of claim 1 combined with a pharmaceutical carrier in dosage unit form.
Claim 6
Dependent Claim
34 words
The method of inducing antihypertensive activity in a subject in need thereof without excess sedation comprising administering to said subject, orally, anally or parenterally, an antihypertensive, nontoxic quantity of a compound of claim 1.
References Cited (Backward Citations)
US3236857A
Cited
US3454701A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-04-24 | 1987-10-24 | 1988-04-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-04-24 | 1991-10-24 | 1992-04-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-04-24 | 1995-10-24 | 1996-04-24 | $7700.00 | Window Closed / Lapsed |