1(2H)-Isoquinolone compounds and acid addition salts thereof

Claim 1

A 1(2H)-isoquinolone compound represented by the formula (I) ##STR7## wherein n is 0 or an integer of 1, R represents a methyl group or a hydroxy group, R 1 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 3 to 4 carbon atoms, or an alkynyl group having 3 to 4 carbon atoms, and R 2 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 3 to 4 carbon atoms, an alkynyl group having 3 to 4 carbon atoms, a benzyl group, an ethoxycarbonyl group, a mono- or dialkylcarbamoyl having 1 to 4 carbon atoms in each alkyl group, an acetyl group, a mono- or dialkylaminoethoxyacetyl group or a group of the formula ##STR8## wherein R 3 and R 4 , which may be the same or different, each represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a hydroxyalkyl group having 2 to 4 carbon atoms or an allyl group, or R 3 and R 4 , when taken together with nitrogen atom to which they are attached, represent a heterocyclic group selected from the group consisting of a pyrrolidino group, a piperazino group, a 4-methylpiperazino group, a piperidino group and a morpholino group, with the proviso that, when R represents a methyl group, ##STR9## cannot be a monoalkylamino group or a dialkylamino group and when R represents a hydroxy group, n represents an integer of 1; and the acid addition salt thereof.