US4432986A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tetrazoles bonded to certain polycyclic aromatic systems and anti-allergic use thereof
Assignee: Riker Laboratories Inc
•
Filing: 1982-03-23
•
Granted: 1984-02-21
•
Expires: 2002-03-23
Abstract
Abstract Amides obtained by reaction of aminotetrazole and certain optionally substituted polycyclic aromatic acids are potent anti-allergic agents.
Inventors
- 👤 Edward H. Erickson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 16:22
CPC Classifications
C; C07; C07D; C07D405/00; C07D405/02; C07D405/12; C07C; C07C65/00; C07C65/21; C07C65/24; C07D257/00; C07D257/02; C07D257/04; C07D257/06; C07D409/00; C07D409/02; C07D409/12
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
22 words
A compound of the formula ##STR8## wherein R is hydrogen or lower (C 1-4 ) alkyl and Ar is selected from ##STR9##
Claim 2
Dependent Claim
22 words
A compound of the formula ##STR8## wherein R is hydrogen or lower (C 1-4 ) alkyl and Ar is selected from ##STR9##
Claim 3
Dependent Claim
9 words
Compounds according to claim 1, wherein R is hydrogen.
Claim 4
Dependent Claim
7 words
The compound N-(tetrazol-5-yl)dibenzothiophene-4-carboxamide according to claim 2.
Claim 5
Dependent Claim
7 words
The compound N-(tetrazol-5-yl)dibenzofuran-4-carboxamide according to claim 2.
Claim 6
Dependent Claim
7 words
The compound 3-methoxy-N-(tetrazol-5-yl)naphthalene-2-carboxamide according to claim 2.
Claim 7
Dependent Claim
11 words
A compound according to claim 1, wherein R is lower alkyl.
Claim 8
Dependent Claim
10 words
A compound according to claim 1, wherein R is methyl.
Claim 9
Dependent Claim
19 words
An anti-allergic composition, comprising an effective amount of a compound according to claim 1 and a pharmaceutically acceptable carrier.
Claim 10
Dependent Claim
19 words
Compositions according to claim 8, wherein said compound is selected from the group consisting of: N-(tetrazol-5-yl)dibenzothiophene-4-carboxamide, N-(tetrazol-5-yl)dibenzofuran-4-carboxamide, and 3-methoxy-N-(tetrazol-5-yl)naphthalene-2-carboxamide.
Claim 11
Dependent Claim
28 words
A method for inhibiting asthmatic reactions in a mammal which comprises administering to said mammal a pharmaceutically effective amount of at least one composition according to claim 8.
Claim 12
Dependent Claim
14 words
A method according to claim 10, wherein the method of administration is by inhalation.
Claim 13
Dependent Claim
13 words
A method according to claim 10, wherein the method of administration is oral.
Claim 14
Dependent Claim
21 words
A method according to claim 10, in which said compound is selected from the group consisting of: N-(tetrazol-5-yl)dibenzothiophene-4-carboxamide, N-(tetrazol-5-yl)dibenzofuran-4-carboxamide, and 3-methoxy-N-(tetrazol-5-yl)naphthalene-2-carboxamide.
References Cited (Backward Citations)
US3642997A
Cited
US3887574A
Cited
US3905989A
Cited
US4145350A
Cited
US3975403A
Cited
US4146631A
Cited
US4147694A
Cited
US4232024A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-02-20 | 1987-08-22 | 1988-02-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-02-20 | 1991-08-22 | 1992-02-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-02-20 | 1995-08-22 | 1996-02-21 | $7700.00 | Window Closed / Lapsed |