Thixotropic compositions easily convertible to pourable liquids

Claim 2

An aqueous vehicle composition comprising water and (a) from about 1% to about 3% weight/volume of a suspendeding agent consisting of about 89% weight microcrystalline cellulose gel blended with about 11 weight percent sodium carboxymethylcellulose, and (b) from about 0.01% to about 0.5% weight/volume titanium dioxide, which composition is a thixotropic gel on standing but is easily convertable to a pourable liquid upon moderate shaking for about five seconds.

Claim 3

A composition of claim 1 wherein the suspending agent is present in an amount of from about 1% to about 2% weight/volume and the titanium dioxide is present in an amount of from about 0.025% to about 0.1% weight/volume.

Claim 4

A composition of claim 2 wherein the suspending agent is present in an amount of about 11/2% weight/volume and the titanium dioxide is present in an amount of about 0.1% weight/volume.

Claim 5

A composition of claim 1 having a viscosity upon standing measured at 25° C. of from about 6,000 to about 8,000 cps and, after moderate shaking for about five seconds, a viscosity at 25° C. of from about 300 to about 800 cps.

Claim 6

A composition of claim 2 having a viscosity upon standing measured at 25° C. of from about 6,000 to about 8,000 cps and, after moderate shaking for about five seconds, a viscosity at 25° C. of from about 300 to about 800 cps.

Claim 7

A composition of claim 3 having a viscosity upon standing measured at 25° C. of from about 6,000 to about 8,000 cps and, after moderate shaking for about five seconds, a viscosity at 25° C. of from about 300 to about 800 cps.

Claim 8

A composition of claim 1 which is a cough/sore throat liquid composition.

Claim 9

A composition of claim 1 which is a throat coating cough medicine.

Claim 10

A composition of claim 1 comprising the following composition. ______________________________________ Ingredients Amount/15 ml Dose ______________________________________ Dextromethorphan HBr 15.0 mg Acetaminophen 650.0 mg Sugar 15.3 g Microcrystalline Cellulose and 375.0 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 156.6 mg Citric Acid, Anhydrous 101.4 mg Sodium Benzoate 30.0 mg Sorbitol Solution 600.0 mg Glycerine 600.0 mg Titanium dioxide 30.0 mg Propylene Glycol 3.6 g Alcohol, 95% (abs) 3.0 ml Flavorant 10.35 mg Menthol 36.0 mg Colorant 0.72 mg Water, Purified, q.s. 30.0 ml ______________________________________

Claim 11

A composition of claim 1 comprising the following composition: ______________________________________ Ingredients Amount/15 ml Dose ______________________________________ Guaifenesin 200.0 mg Sugar 7.65 g Microcrystalline Cellulose and 187.5 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 78.3 mg Citric Acid, Anhydrous 50.7 mg Sodium Benzoate 15.0 mg Sorbitol Solution 300.0 mg Glycerin 300.0 mg Titanium dioxide 15.0 mg Propylene Glycol 1.8 g Alcohol, 95% (abs) 1.5 ml Flavorants 15.0 μl Menthol 12.0 mg Colorants 3.75 mg Water, Purified, q.s. 15.0 ml. ______________________________________

Claim 12

A composition of claim 1 comprising the following composition: ______________________________________ Ingredients Amount/30 ml Dose ______________________________________ Dextromethorpham HBr 10.0 mg Acetaminophen 480.0 mg Sugar 15.3 g Microcrystalline Cellulose and 375.0 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 156.6 mg Citric Acid, Anhydrous 101.4 mg Sodium Benzoate 30.0 mg Sodium Saccharin 12.0 mg Sorbitol Solution 600.0 mg Glycerin 600.0 mg Titanium dioxide 30.0 mg Propylene Glycol 4.5 g Alcohol, 95% (abs) 2.25 ml Flavorant 0.0375 ml Menthol 12.0 mg Colorant 0.60 mg Water, Purified, q.s. 30.0 ml. ______________________________________

Claim 13

A composition of claim 1 comprising the following composition: ______________________________________ Ingredients Amount/15 ml Dose ______________________________________ Dextromethorphan HBr 30.0 mg Sugar 7.65 g Microcrystalline Cellulose and 187.5 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 78.3 mg Citric Acid, Anhydrous 50.7 mg Sodium Benzoate 15.0 mg Sorbitol Solution 300.0 mg Glycerin 300.0 mg Titanium dioxide 15.0 mg Propylene Glycol 1.8 g Alcohol, 95% (abs) 1.5 ml Flavorant 37.5 μl Menthol 12.0 mg Colorant 3.0 mg Water, Purified, q.s. 15.0 ml. ______________________________________

Claim 14

A composition of claim 1 comprising the following composition: ______________________________________ Ingredients Amount/15 ml Dose ______________________________________ Guaifenesin 200.0 mg Phenylpropanolamine HCl 37.5 mg Dextromethorphan HBr 20.0 mg Sugar 7.65 g Microcrystalline Cellulose and 187.5 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 300.0 mg Citric Acid, Anhydrous 3.5 mg Sodium Benzoate 15.0 mg Sorbitol Solution 300.0 mg Glycerin 300.0 mg Titanium dioxide 15.0 mg Propylene Glycol 1.8 g Alcohol, 95% (abs) 1.5 ml Flavorant 15.0 μl Menthol 12.0 mg Colorants 1.53 mg Water, Purified, q.s. 15.0 ml. ______________________________________

Claim 15

A composition of claim 1 comprising the following composition: ______________________________________ Ingredients Amount/15 ml Dose ______________________________________ Phenylpropanolamine HCl 37.5 mg Dextromethorphan HBr 20.0 mg Doxylamine Succinate 7.5 mg Sugar 7.65 g Microcrystalline Cellulose and 187.5 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 300.0 mg Citric Acid, Anhydrous 3.5 mg Sodium Benzoate 15.0 mg Sorbitol Solution 300.0 mg Glycerin 300.0 mg Titanium dioxide 15.0 mg Propylene Glycol 1.8 g Alcohol, 95% (abs) 1.5 ml Flavorant 37.5 μl Menthol 12.0 mg Colorant 0.3 mg Water, Purified, q.s. 15.0 ml. ______________________________________

Claim 16

A composition of claim 1 comprising the following composition: ______________________________________ Ingredients Amount/15 ml Dose ______________________________________ Dextromethorphan HBr 15.0 mg Doxylamine Succinate 7.5 mg Sugar 7.65 g Microcrystalline Cellulose and 187.5 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 78.3 mg Citric Acid, Anhydrous 15.0 mg Sodium Benzoate 15.0 mg Sorbitol Solution 300.0 mg Glycerin 300.0 mg Titanium dioxide 15.0 mg Propylene Glycol 2.25 g Alcohol, 95% (abs) 1.5 ml Menthol 11.25 mg Flavorants 8.0 mg Colorant 0.054 mg Water, Purified, q.s. 15.0 ml. ______________________________________

Claim 17

A composition of claim 1 comprising the following composition: ______________________________________ Ingredients Amount/15 ml Dose ______________________________________ Guaifenesin 200.0 mg Phenylpropanolamine HCl 25.0 mg Dextromethorphan HBr 20.0 mg Microcrystalline Cellulose and 187.5 mg Sodium CMC (Avicel ® RC-591, FMC) Sodium Citrate, Hydrous 300.0 mg Citric Acid, Anhydrous 3.5 mg Sodium Benzoate 15.0 mg Sorbitol Solution 300.0 mg Glycerin 300.0 mg Titanium dioxide 15.0 mg Propylene Glycol 2.25 g Alcohol, 95% (abs) 1.5 ml Flavorant 25.5 μl Menthol 18.0 mg Colorant 3.0 mg Sugar 10.2 g Water, Purified, q.s. 15.0 ml. ______________________________________