US4413771A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for centrifugal separation
Assignee: Bank of America NA
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Filing: 1979-09-10
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Granted: 1983-11-08
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Expires: 1999-09-10
Abstract
Abstract A blood bag is described which aids in maintaining the separation of blood components. This bag is constructed of a flexible plastic, has a conical top leading to an outlet line and internal septa to reduce swirling of the bag's contents during rotor deceleration. The bag is adapted to be placed in a split sleeve prior to placement in the swinging bucket of a centrifuge rotor. A collar is placed over the top of the bag to aid in reducing wrinkles in the bag. Methods are described for reducing contamination of separated blood components by reducing bag wrinkles, reducing swirling of the blood fractions during rotor deceleration, and reducing mixing during expression.
Inventors
- 👤 Vernon C. Rohde
- 👤 William A. Romanauskas
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 23:49
CPC Classifications
B; B04; B04B; B04B5/00; B04B5/04; B04B5/0407; B04B5/0428
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
151 words
In a sealed, flexible thermoplastic blood centrifugation container having side wall sections with laminate edge seals and a longitudinal axis, two different portions of said edge seals being generally parallel to said longitudinal axis, and a first tubular conduit means sealed between said wall sections, communicating with the interior of said container and intersecting said longitudinal axis, the improvement wherein: said container includes a septum, defined by a first sheet of a flexible thermoplastic, having ends joined to opposite said side wall sections along laminate seals which are generally parallel to said longitudinal axis, said septum being positioned longitudinally only in the mid portion of said container in the region of said different portions with the top of said septum extending to a point just above the separation line that occurs when blood is separated into plasma on the one hand and packed cells and a buffy coat on the other.
Claim 2
Dependent Claim
151 words
In a sealed, flexible thermoplastic blood centrifugation container having side wall sections with laminate edge seals and a longitudinal axis, two different portions of said edge seals being generally parallel to said longitudinal axis, and a first tubular conduit means sealed between said wall sections, communicating with the interior of said container and intersecting said longitudinal axis, the improvement wherein: said container includes a septum, defined by a first sheet of a flexible thermoplastic, having ends joined to opposite said side wall sections along laminate seals which are generally parallel to said longitudinal axis, said septum being positioned longitudinally only in the mid portion of said container in the region of said different portions with the top of said septum extending to a point just above the separation line that occurs when blood is separated into plasma on the one hand and packed cells and a buffy coat on the other.
Claim 3
Dependent Claim
22 words
A storage container according to claim 1 wherein the edge seals are tapered from said different portions to said first conduit means.
Claim 4
Dependent Claim
27 words
A container according to claim 2 wherein the taper angle between said edge seals lies between 25° and 160°, thereby to provide a generally conical container top.
Claim 5
Dependent Claim
13 words
A container according to claim 3 wherein said taper angle is about 75°.
Claim 6
Dependent Claim
54 words
A container according to claim 1, 2 or 4 wherein said septum is defined by first and second sheets of a flexible thermoplastic each having selected ends joined to selected side wall sections and each being joined together along their mid portions, the jointures occurring along laminate seals generally parallel to said longitudinal axis.
Claim 7
Dependent Claim
53 words
A container according to claim 2 or 4 wherein the upper portion of each of said side wall sections in the region of taper are double pyramidal shaped and their edges joined with an additional pair of laminate edge seals so that the taper portion of said container approximates a cone when filled.
Claim 8
Dependent Claim
110 words
A sealed, plastic blood centrifuge container, generally cylindrical when filled with blood, said container having a longitudinal axis and a top and bottom, and a first tubular conduit communicating with the interior of said container, characterized by an interior septum lying in a plane generally parallel to said longitudinal axis, thereby to reduce movement of a fluid in said container during centrifugation, said septum extending along said longitudinal axis from a point just above said bottom to a point below said conical top just above the separation line that occurs when blood is separated into plasma on the one hand and packed cells and a buffy coat on the other.
Claim 9
Dependent Claim
110 words
A sealed, plastic blood centrifuge container, generally cylindrical when filled with blood, said container having a longitudinal axis and a top and bottom, and a first tubular conduit communicating with the interior of said container, characterized by an interior septum lying in a plane generally parallel to said longitudinal axis, thereby to reduce movement of a fluid in said container during centrifugation, said septum extending along said longitudinal axis from a point just above said bottom to a point below said conical top just above the separation line that occurs when blood is separated into plasma on the one hand and packed cells and a buffy coat on the other.
Claim 10
Dependent Claim
14 words
A container according to claim 7, wherein said conduit lies on said longitudinal axis.
Claim 11
Dependent Claim
31 words
A container according to claim 8 wherein the top of said container is tapered in a generally conical configuration converging at said first conduit, thereby to reduce fluid intermixing during expression.
Claim 12
Dependent Claim
20 words
A container according to claim 9 wherein said top portion is curvilinear with a decreasing taper toward said first conduit.
Claim 13
Dependent Claim
23 words
A container according to claim 9 which includes a second tubular conduit communicating with the interior of said container as the bottom thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-11-07 | 1987-05-09 | 1987-11-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-11-07 | 1991-05-09 | 1991-11-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-11-07 | 1995-05-09 | 1995-11-08 | $7700.00 | Window Closed / Lapsed |