US4411909A
Expired / Lapsed
US
⏱️ 0.0 years remaining
[(2-Oxo-3-tetrahydrothienylcarbamoyl)-alkylthio] acetic acids, their salts and esters, a process for preparation thereof and the pharmaceutical compositions containing same
Assignee: REFARMED RECHERCHES PHARMACEUTIQUES ET MEDICALES SA
•
Filing: 1982-03-15
•
Granted: 1983-10-25
•
Expires: 2002-03-15
Abstract
Abstract The present invention relates to [(2-oxo-3-tetrahydrothienylcarbamoyl)-alkylthio]-acetic acids, their salts and esters of formula: ##STR1## in which n is 0 or 1, one of the substituents R 1 and R 2 is a hydrogen atom or a methyl group and the other represents a group -S-CH 2 -COOR 3 , where R 3 is a hydrogen atom or an alkali metal or a lower alkyl group or a group: ##STR2## It also relates to a process for preparing said acids, salts and esters, and to the drugs containing same.
Inventors
- 👤 Jacques Gonella
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 16:26
CPC Classifications
C; C07; C07D; C07D333/00; C07D333/02; C07D333/04; C07D333/26; C07D333/30; C07D333/36; A; A61; A61P; A61P11/00; A61P11/10; A61P27/00; A61P27/16
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
92 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-alkylthio]-acetic acid, salt or ester, or formula: ##STR6## in which n represents 0 or 1 and one of the substituents R 1 and R 2 represents a hydrogen atom or a methyl group and the other represents a --S--CH 2 --COOR 3 group, where R 3 is a hydrogen atom or an alkali metal or a group R 3 ', R 3 ' being a lower alkyl or a group: ##STR7## where m represents 0 or 1 and X represents a hydrogen atom, or a lower alkyl, lower alkoxy or nitro group.
Claim 2
Dependent Claim
92 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-alkylthio]-acetic acid, salt or ester, or formula: ##STR6## in which n represents 0 or 1 and one of the substituents R 1 and R 2 represents a hydrogen atom or a methyl group and the other represents a --S--CH 2 --COOR 3 group, where R 3 is a hydrogen atom or an alkali metal or a group R 3 ', R 3 ' being a lower alkyl or a group: ##STR7## where m represents 0 or 1 and X represents a hydrogen atom, or a lower alkyl, lower alkoxy or nitro group.
Claim 3
Dependent Claim
12 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetic acid of formula: ##STR8## and the sodium and potassium salts thereof.
Claim 4
Dependent Claim
12 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetic acid of formula: ##STR8## and the sodium and potassium salts thereof.
Claim 5
Dependent Claim
3 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetate of ethyl.
Claim 6
Dependent Claim
3 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetate of ethyl.
Claim 7
Dependent Claim
3 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetate of phenyl.
Claim 8
Dependent Claim
3 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetate of phenyl.
Claim 9
Dependent Claim
3 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetate of 2-methoxyphenyl.
Claim 10
Dependent Claim
3 words
[(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetate of 2-methoxyphenyl.
Claim 11
Dependent Claim
17 words
Pharmaceutical composition containing, as active ingredient, a compound according to claim 1 mixed with a pharmaceutical excipient.
Claim 12
Dependent Claim
28 words
The pharmaceutical composition of claim 6, in dosage unit form, containing from 1 to 1000 mg of the compound according to claim 1 mixed with a pharmaceutical excipient.
Claim 13
Dependent Claim
22 words
The pharmaceutical composition of claims 6 or 7, wherein it contains, as active ingredient, [(2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio]-acetic acid or its sodium or potassium salt.
References Cited (Backward Citations)
US4241078A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-10-24 | 1987-04-25 | 1987-10-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-10-24 | 1991-04-25 | 1991-10-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-10-24 | 1995-04-25 | 1995-10-25 | $7700.00 | Window Closed / Lapsed |