US4409233A
Expired / Lapsed
US
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Highly concentrated preparations of dopa compounds
Assignee: Sankyo Co Ltd
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Filing: 1979-07-02
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Granted: 1983-10-11
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Expires: 1999-07-02
Abstract
Abstract A highly concentrated aqueous composition of a dopa which comprises a dopa and at least one amino acid selected from the group consisting of methionine, proline, hydroxyproline, serine, threonine, valine, arginine, lysine, histidine and ornithine. Said composition having a concentration of said amino acid of 1-300 mg per ml of said aqueous solution of a dopa compound.
Inventors
- 👤 Kazuhiro Tsukada
- 👤 Wataru Kato
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 07:28
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K47/00; A61K47/06; A61K47/16; A61K47/18; A61K47/183; A61K47/20; A61P; A61P25/00; A61P9/00; A61P9/12
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
53 words
A highly concentrated aqueous composition of a dopa which comprises a dopa and at least one amino acid selected from the group consisting of methionine, proline, hydroxyproline, serine, threonine, valine, arginine, lysine, histidine and ornithine, said composition having a concentration of said amino acid of 1-300 mg per ml of said aqueous composition.
Claim 2
Dependent Claim
53 words
A highly concentrated aqueous composition of a dopa which comprises a dopa and at least one amino acid selected from the group consisting of methionine, proline, hydroxyproline, serine, threonine, valine, arginine, lysine, histidine and ornithine, said composition having a concentration of said amino acid of 1-300 mg per ml of said aqueous composition.
Claim 3
Dependent Claim
10 words
The composition of claim 1 wherein said dopa is L-3-(3,4-dihydroxyphenyl)-2-methylalanine.
Claim 4
Dependent Claim
10 words
The composition of claim 1 wherein said dopa is β-(3,4-dihydroxyphenyl)-α-alanine.
Claim 5
Dependent Claim
11 words
The composition of claim 3 wherein said amino acid is arginine.
Claim 6
Dependent Claim
11 words
The composition of claim 3 wherein said amino acid is lysine.
Claim 7
Dependent Claim
11 words
The composition of claim 3 wherein said amino acid is histidine.
Claim 8
Dependent Claim
11 words
The composition of claim 3 wherein said amino acid is ornithine.
Claim 9
Dependent Claim
11 words
The composition of claim 2 wherein said amino acid is arginine.
Claim 10
Dependent Claim
11 words
The composition of claim 2 wherein said amino acid is lysine.
Claim 11
Dependent Claim
11 words
The composition of claim 2 wherein said amino acid is histidine.
Claim 12
Dependent Claim
11 words
The composition of claim 2 wherein said amino acid is ornithine.
Claim 13
Dependent Claim
11 words
The composition of claim 1 wherein said amino acid is arginine.
Claim 14
Dependent Claim
11 words
The composition of claim 1 wherein said amino acid is lysine.
Claim 15
Dependent Claim
11 words
The composition of claim 1 wherein said amino acid is histidine.
Claim 16
Dependent Claim
11 words
The composition of claim 1 wherein said amino acid is ornithine.
Claim 17
Dependent Claim
63 words
A freeze-dried composition of a dopa which comprises a dopa and at least one amino acid selected from the group consisting of methionine, proline, hydroxyproline, serine, threonine, valine, arginine, lysine, histidine and ornithine, said composition having been prepared by freeze-drying a concentrated aqueous composition comprising said dopa and said amino acid in an amount of 1-300 mg per ml of said aqueous composition.
Claim 18
Dependent Claim
63 words
A freeze-dried composition of a dopa which comprises a dopa and at least one amino acid selected from the group consisting of methionine, proline, hydroxyproline, serine, threonine, valine, arginine, lysine, histidine and ornithine, said composition having been prepared by freeze-drying a concentrated aqueous composition comprising said dopa and said amino acid in an amount of 1-300 mg per ml of said aqueous composition.
References Cited (Backward Citations)
US3911137A
Cited
US4321264A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-10-10 | 1987-04-11 | 1987-10-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-10-10 | 1991-04-11 | 1991-10-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-10-10 | 1995-04-11 | 1995-10-11 | $7700.00 | Window Closed / Lapsed |