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US4407793A Expired / Lapsed US ⏱️ 0.0 years remaining

Composition for temporary substitution of bone tissue defects

Assignee: Individual
•
Filing: 1982-05-26
•
Granted: 1983-10-04
•
Expires: 2002-05-26
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Abstract

Abstract The composition for a temporary substitution of bone tissue defects according to the present invention consists of α-cyanacrylic acid esters and a powder-like filler which is a calcium salt of an organic or inorganic acid with a particle size of from 0.01 to 0.5 mm, the components being used in the following proportions, percent by weight: ______________________________________ α-cyanacrylic acid esters 60 to 40 calcium salt of organic or inorganic acid with a particle size of 0.01 to 0.5 mm 40 to 60. ______________________________________ The composition of the present invention is useful for fixation of bone fragments, fixation of bone homotransplantant in the case of anterior cervical spondyolodosis, temporary filling of bone cavities and the like.

Inventors

  • 👤 Alla Y. Akimova
  • 👤 Anatoly B. Davydov
  • 👤 Galina M. Derkach
  • 👤 Valeria I. Timokhina
  • 👤 Sergei S. Tkachenko
  • 👤 Vladimir V. Rutsky
  • 👤 Mstislav V. Volkov
  • 👤 Irina S. Shepeleva
  • 👤 Alexandr V. Shiryaev
  • 👤 Semen I. Lipkin
  • 👤 Vladimir M. Musyanovich

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 19:23
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/40; A61L27/44; A61L27/446; A61K; A61K6/00; A61K6/80; A61K6/884; A61K6/887; C; C09; C09J; C09J4/00

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 101 words
A composition for a temporary substitution of bone tissue defects comprising α-cyanacrylic acid esters and a powder-like filler selected from the group consisting of a calcium salt of an organic acid and a calcium salt of an inorganic acid with a particle size of from 0.01 to 0.5 mm at the following proportions of the components, percent by weight: ______________________________________ cyanacrylic acid esters 60 to 40 powder-like filler selected from the group con- sisting of calcium salt of an organic acid and calcium salt of inorganic acid with a particle size of from 0.01 to 0.5 mm 40 to 60. ______________________________________
Claim 2
Dependent Claim 101 words
A composition for a temporary substitution of bone tissue defects comprising α-cyanacrylic acid esters and a powder-like filler selected from the group consisting of a calcium salt of an organic acid and a calcium salt of an inorganic acid with a particle size of from 0.01 to 0.5 mm at the following proportions of the components, percent by weight: ______________________________________ cyanacrylic acid esters 60 to 40 powder-like filler selected from the group con- sisting of calcium salt of an organic acid and calcium salt of inorganic acid with a particle size of from 0.01 to 0.5 mm 40 to 60. ______________________________________
Claim 3
Dependent Claim 27 words
A composition as claimed in claim 1, wherein as the calcium salt a salt is used selected from the group consisting of calcium gluconate and calcium carbonate.
Claim 4
Dependent Claim 24 words
A composition as claimed in claim 1, wherein a regeneration stimulant is additionally incorporated in an amount of from 10 to 30% by weight.
Claim 5
Dependent Claim 29 words
A composition as claimed in claim 3, wherein as the regeneration stimulant use is made of a compound selected from the group consisting of 4-uracylcarboxylic acid and derivatives thereof.
Claim 6
Dependent Claim 23 words
A composition as claimed in claim 1, wherein an antiseptic is additionally incorporated in an amount of from 10 to 30% by weight.
Claim 7
Dependent Claim 20 words
A composition as claimed in claim 5, wherein as the antiseptic use is made of 1,4-di-N-oxy 2,3-dihydroxymethylquinoxaline or 1,4-di-N-oxy 2,3-diacetoxymethylquinoxaline.
Claim 8
Dependent Claim 24 words
A composition as claimed in claim 1, wherein as the esters of α-cyanacrylic acid use is made of a mixture of ethyl-α-cyanacrylate and ethoxyethyl-α-cyanacrylate.

References Cited (Backward Citations)

US4093576A Cited
US4192021A Cited
US4239113A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-10-03 1987-04-04 1987-10-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-10-03 1991-04-04 1991-10-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-10-03 1995-04-04 1995-10-04 $7700.00 Window Closed / Lapsed

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