US4406884A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Topical antimicrobial composition
Assignee: Procter and Gamble Co
•
Filing: 1981-06-23
•
Granted: 1983-09-27
•
Expires: 2001-06-23
Abstract
Abstract Topical antimicrobial compositions in the form of an aqueous gel or lotion are disclosed; these compositions contain C 5 -C 12 fatty acids and have a pH no greater than about 5. The compositions provide excellent broad-spectrum antimicrobial performance and, in fact, are more effective than similar compositions formulated as creams, ointments, non-aqueous lotions or non-aqueous gels. The method of treating skin disorders of pathogenic origin using these compositions is also disclosed.
Inventors
- 👤 Mahdi B. Fawzi
- 👤 Melvin A. Barbera
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 10:54
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/185; A61K31/19; A61K31/20; A61K47/00; A61K47/30; A61K47/32
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
47 words
A topical pharmaceutical composition in the form of an aqueous lotion or aqueous gel, having a pH no greater than about 5, comprising a safe and effective amount of an antimicrobial agent selected from the group consisting of C 5 -C 12 fatty acids and mixtures thereof.
Claim 2
Dependent Claim
47 words
A topical pharmaceutical composition in the form of an aqueous lotion or aqueous gel, having a pH no greater than about 5, comprising a safe and effective amount of an antimicrobial agent selected from the group consisting of C 5 -C 12 fatty acids and mixtures thereof.
Claim 3
Dependent Claim
18 words
A composition according to claim 1 which contains from about 0.5% to about 20% of the antimicrobial agent.
Claim 4
Dependent Claim
25 words
A composition according to claim 2 in the form of an aqueous gel which contains from about 0.25% to about 10% of a gelling agent.
Claim 5
Dependent Claim
20 words
A composition according to claim 3 which additionally contains from about 1% to about 99.5% of a pharmaceutically-acceptable topical carrier.
Claim 6
Dependent Claim
26 words
A composition according to claim 4 wherein the antimicrobial agent is selected from the group consisting of C 6 -C 10 fatty acids and mixtures thereof.
Claim 7
Dependent Claim
24 words
A composition according to claim 5 wherein the antimicrobial agent is selected from the group consisting of octanoic acid, decanoic acid, and mixtures thereof.
Claim 8
Dependent Claim
18 words
A composition according to claim 6 which contains from about 1% to about 10% of the antimicrobial agent.
Claim 9
Dependent Claim
15 words
A composition according to claim 6 wherein the gelling agent is an acidic carboxy polymer.
Claim 10
Dependent Claim
24 words
A composition according to claim 1 wherein the antimicrobial agent is selected from the group consisting of octanoic acid, decanoic acid, and mixtures thereof.
Claim 11
Dependent Claim
13 words
A composition according to claim 9 wherein the antimicrobial agent is octanoic acid.
Claim 12
Dependent Claim
14 words
A composition according to claim 1 having a pH no greater than about 4.
Claim 13
Dependent Claim
14 words
A composition according to claims 1 or 9 containing at least about 15% water.
Claim 14
Dependent Claim
37 words
A method of treating skin conditions of bacterial, yeast or fungal origin in humans or animals comprising the topical application to the afflicted situs of a safe and effective amount of the composition according to claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-09-26 | 1987-03-28 | 1987-09-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-09-26 | 1991-03-28 | 1991-09-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-09-26 | 1995-03-28 | 1995-09-27 | $7700.00 | Window Closed / Lapsed |