US4404845A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Thermal regulator for liquid chromatographs
Assignee: Agilent Technologies Deutschland GmbH
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Filing: 1981-06-22
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Granted: 1983-09-20
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Expires: 2001-06-22
Abstract
Abstract A thermostat arrangement for the mobile phase and the separation column in a liquid chromatograph comprises a heat exchanger through which the mobile phase passes. The heat exchanger has a heating and/or cooling element and is arranged between a sample injection device and the entrance of the separation column. The heat exchanger serves to selectively heat or cool the ambient air surrounding the separation column.
Inventors
- 👤 Helge Schrenker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 07:30
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/26; G01N30/28; G01N30/30; G01N2030/3084
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
158 words
A thermal regulator for the mobile phase and the separation column in a liquid chromatograph having a sample injection device, said thermal regulator comprising: a heat exchanger including a capillary tube through which the mobile phase passes, said heat exchanger being disposed between the sample injection device and the entrance of the separation column and containing a heating element and a cooling element for respectively heating and cooling ambient air surrounding the separation column; said capillary tube, said heating element and said cooling element being sealed within a molded radiator body of heat conducting material disposed in contact with ambient air surrounding said separation column; said capillary tube having an inner diameter of less than 0.15 mm and a volume of less than 2 μl within the heat exchanger; whereby a variation of the flow rate of the mobile phase within a range of 0 to 5 ml/min causes a temperature deviation of less than ±2 degrees C.
Claim 2
Dependent Claim
158 words
A thermal regulator for the mobile phase and the separation column in a liquid chromatograph having a sample injection device, said thermal regulator comprising: a heat exchanger including a capillary tube through which the mobile phase passes, said heat exchanger being disposed between the sample injection device and the entrance of the separation column and containing a heating element and a cooling element for respectively heating and cooling ambient air surrounding the separation column; said capillary tube, said heating element and said cooling element being sealed within a molded radiator body of heat conducting material disposed in contact with ambient air surrounding said separation column; said capillary tube having an inner diameter of less than 0.15 mm and a volume of less than 2 μl within the heat exchanger; whereby a variation of the flow rate of the mobile phase within a range of 0 to 5 ml/min causes a temperature deviation of less than ±2 degrees C.
Claim 3
Dependent Claim
34 words
A thermal regulator according to claim 1, wherein a temperature sensor is mounted on the surface of the radiator body close to the capillary tube and to the heating element and the cooling element.
References Cited (Backward Citations)
US3165147A
Cited
US3522725A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-09-19 | 1987-03-21 | 1987-09-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-09-19 | 1991-03-21 | 1991-09-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-09-19 | 1995-03-21 | 1995-09-20 | $7700.00 | Window Closed / Lapsed |