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US4404192A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for preparing compositions for perfusing artificial kidney systems for dialysis

Assignee: TOMITA PHARMACEUTICAL Corp Ltd A CORPOF JAPAN
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Filing: 1980-08-20
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Granted: 1983-09-13
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Expires: 2000-08-20
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Abstract

Abstract PCT No. PCT/JP80/00186 Sec. 371 Date Apr. 27, 1981 Sec. 102(e) Date Apr. 14, 1981 PCT Filed Aug. 20, 1980 PCT Pub. No. WO81/00515 PCT Pub. Date Mar. 5, 1981.A process for preparing a composition having low hygroscopicity, in the form of uniform particles and useful for perfusing artificial kidney systems from compounds to give an electrolyte ion composition comprising Na+, K+, Ca++, Mg++, C1- and CH3COO- ions in specified proportions, the process being characterized by dissolving the compounds in warm water, allowing the solution to stand for at least 6 hours and thereafter spray-drying the resulting aqueous solution of mixed salts by spraying the solution into a drying chamber having an inlet temperature of 200 DEG to 400 DEG C. from the orifice of a pressurized nozzle having an orifice diameter of 1.0 to 2.0 mm.

Inventors

  • 👤 Takeshi Suzuki

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 18:50
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1654; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1682; A61K9/1688; A61M1/1656; A61M1/1666; A61P; A61P7/00

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 144 words
A process for preparing a composition having low hygroscopicity, in the form of uniform particles and useful for perfusing artificial kidney systems from compounds to give an electrolyte ion composition comprising 126-145 mEq/l of Na + , 1.5--3.0 mEq/l of K + , 2.5-4.0 mEq/l of Ca ++ , 1.0-1.5 mEq/l of Mg ++ , 98-108 mEq/l of Cl - and 30-4.52 mEq/l of CH 3 COO - , said process comprising dissolving the compounds in warm water having a temperature of about 35° to 40° C., allowing the solution to stand for at least 6 hours, and thereafter spray-drying the resulting aqueous solution of mixed salts by spraying the solution into a drying chamber having an inlet temperature of 200° to 400° C. from the orifice of a spray nozzle having an orifice diameter of 1.0 to 2.0 mm to form said composition.
Claim 2
Dependent Claim 144 words
A process for preparing a composition having low hygroscopicity, in the form of uniform particles and useful for perfusing artificial kidney systems from compounds to give an electrolyte ion composition comprising 126-145 mEq/l of Na + , 1.5--3.0 mEq/l of K + , 2.5-4.0 mEq/l of Ca ++ , 1.0-1.5 mEq/l of Mg ++ , 98-108 mEq/l of Cl - and 30-4.52 mEq/l of CH 3 COO - , said process comprising dissolving the compounds in warm water having a temperature of about 35° to 40° C., allowing the solution to stand for at least 6 hours, and thereafter spray-drying the resulting aqueous solution of mixed salts by spraying the solution into a drying chamber having an inlet temperature of 200° to 400° C. from the orifice of a spray nozzle having an orifice diameter of 1.0 to 2.0 mm to form said composition.
Claim 3
Dependent Claim 20 words
A process as claimed in claim 1 wherein the aqueous solution of mixed salts has a concentration of about 35%.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-09-12 1987-03-14 1987-09-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-09-12 1991-03-14 1991-09-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-09-12 1995-03-14 1995-09-13 $7700.00 Window Closed / Lapsed

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