Cyclic pyrophosphate derivatives and their preparation

Claim 2

A cyclic pyrophosphate derivative having the formula (I): ##STR24## wherein A represents a direct bond between the two phenyl rings or a divalent moiety selected from the group consisting of lower alkylene, aryl substituted lower alkylene, cycloalkylidene, sulfonyl and oxy; R 1 represents allyl, acryloyloxy lower alkyl or methacryloxy lower alkyl, in which the lower alkyl can be substituted with halogen; and R 2 represents independently hydrogen, halogen, lower alkyl or lower alkoxy.

Claim 3

The cyclic pyrophosphate according to claim 1, wherein A is a direct bond between the two penyl rings.

Claim 4

The cyclic pyrophosphate according to claim 1, wherein A is dimethyl methylene.

Claim 5

The cyclic pyrophosphate according to claim 1, wherein A is phenyl methylene.

Claim 6

The cyclic pyrophosphate according to claim 1, wherein A is sulfonyl.

Claim 7

The cyclic pyrophosphate according to claim 1, wherein A is oxy.

Claim 8

The cyclic pyrophosphate according to claim 1, wherein A is cyclohexylidene.

Claim 9

The cyclic pyrophosphate according to claim 1, wherein every R 2 is hydrogen.

Claim 10

The cyclic pyrophosphate according to claim 1, wherein two of the R 2 groups are halogen.

Claim 11

The cyclic pyrophosphate according to claim 1, wherein every R 2 is halogen.

Claim 12

The cyclic pyropshophate according to claim 1, wherein R 1 is allyl.

Claim 13

The cyclic pyrophosphate according to claim 1, wherein R 1 is 2-methacryloyloxy ethyl.

Claim 14

The cyclic pyrophosphate according to claim 1, wherein R 1 is 1-methyl-2-methacryloyloxy ethyl.

Claim 15

The cyclic pyrophosphate according to claim 1, wherein R 1 is 2-halo-3-methacryloyloxy ethyl.

Claim 16

The cyclic pyrophosphate according to claim 1, wherein R 1 is acryloyloxy ethyl.

Claim 17

A process for the production of cyclic pyrophosphate derivatives having the formula (I) ##STR25## wherein A represents a direct bond between the two phenyl rings or a divalent moiety selected from the group consisting of lower alkylene, aryl substituted lower alkylene, cycloalkylidene, sulfonyl and oxy; R 1 represents allyl, acryloyloxy lower alkyl or methacryloyloxy lower alkyl, in which the lower alkyl can be substituted with halogen; and R 2 represents independently hydrogen, halogen, lower alkyl or lower alkoxy; the process comprising: reacting, under anhydrous conditions, a phenol derivative having the formula (II) ##STR26## with a phosphoryl halide to give the phosphoryl dihalide derivative having the formula (III) ##STR27## wherein X is halogen; adding to the phosphoryl dihalide derivative having the formula (III), under anhydrous conditions, an alcohol having the formula R.sup.1 --OH to obtain a phosphoryl halide derivative having the formula (IV) ##STR28## which is then hydrolyzed, in the presence of a base, to provide the cyclic pyrophosphate derivative having the formula (I).

Claim 18

A process for the production of cyclic pyrophosphate derivatives having the formula (I) ##STR25## wherein A represents a direct bond between the two phenyl rings or a divalent moiety selected from the group consisting of lower alkylene, aryl substituted lower alkylene, cycloalkylidene, sulfonyl and oxy; R 1 represents allyl, acryloyloxy lower alkyl or methacryloyloxy lower alkyl, in which the lower alkyl can be substituted with halogen; and R 2 represents independently hydrogen, halogen, lower alkyl or lower alkoxy; the process comprising: reacting, under anhydrous conditions, a phenol derivative having the formula (II) ##STR26## with a phosphoryl halide to give the phosphoryl dihalide derivative having the formula (III) ##STR27## wherein X is halogen; adding to the phosphoryl dihalide derivative having the formula (III), under anhydrous conditions, an alcohol having the formula R.sup.1 --OH to obtain a phosphoryl halide derivative having the formula (IV) ##STR28## which is then hydrolyzed, in the presence of a base, to provide the cyclic pyrophosphate derivative having the formula (I).

Claim 19

The process according to claim 16, wherein the base, present during hydrolysis, is an amine.