Shoe insole having antibacterial and antifungal properties

Claim 2

A shoe insole having antibacterial and antifungal properties comprising a flexible polyurethane foam prepared from a reaction mixture, comprising a polyol, an organic polyisocyanate, a foaming agent, a reaction catalyst and an effective antibacterial and antifungal proportion of a pyridinethione compound selected from the group consisting of: (a) 1-hydroxy-2(1H)-pyridinethione compounds having the formula ##STR2## wherein R represents a member of the group consisting of hydrogen, lower alkyl, lower alkoxy and halo, and n is a positive integer less than 5; and the following salts thereof: alkali metal, alkaline earth metal, aluminum, heavy metal, amine-addition and quarternary ammonium; (b) 2,2'-dithiobis-pyridine-1,1'-dioxide; and (c) adducts of 2,2'-dithiobis-pyridine-1,1'-dioxide, said adducts having the formula (C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t wherein M is an alkaline earth metal selected from the group consisting of calcium, magnesium, barium and strontium, Y is an anion selected from the group consisting of halides, sulfates, nitrates, chlorates and acetates, and t is either 1 or 2.

Claim 3

The shoe insole of claim 1, wherein said polyol is a polyether polyol.

Claim 4

The shoe insole of claim 2, wherein said reaction mixture further comprises a surfactant.

Claim 5

The shoe insole of claim 3, wherein said compound is employed in a proportion ranging from about 0.05 to about 0.5 parts by weight based on 100 parts by weight of total polyol.

Claim 6

The shoe insole of claim 3, wherein said pyridinethione compound is selected from the group consisting of 2-pyridinethiol-1-oxide, sodium salt; bis[1-hydroxy-2(1H)-pyridinethionate-O,S]-(T-4)-zinc; and 2,2'-dithiobis-pyridine-1,1'-dioxide compound with magnesium sulfate (1:1).

Claim 7

The shoe insole of claim 5, wherein said pyridinethione compound is bis[1-hydroxy-2(1H)-pyridinethionato-O,S]-(T-4)-zinc.

Claim 8

The shoe insole of claim 5, wherein said polyether polyol is an oxypropylated polyhydric alcohol having a molecular weight of about 1,000-6,000 and said organic polyisocyanate is toluene diisocyanate.

Claim 9

The shoe insole of claim 7, wherein said polyether polyol is oxypropylated glycerin and said reaction mixture comprises water and a catalyst mixture of an amine and a stannous salt.

Claim 10

The shoe insole of claim 3, wherein said polyurethane foam is a compression-densified polyurethane foam having a density within the range from about 1.5 to about 15 pounds per cubic foot.

Claim 11

The shoe insole of claim 9, wherein: said pyridinethione compound is selected from the group consisting of 2-pyridinethiol-1-oxide, sodium salt; bis[1-hydroxy-2(1H)-pyridinethionato-O,S]-(T-4)-zinc; and 2,2'-dithiobis-pyridine-1,1'-dioxide compound with magnesium sulfate (1:1); said polyether polyol is an oxypropylated polyhydric alcohol having a molecular weight of about 1,000-6,000; and said organic polyisocyanate is toluene diisocyanate.

Claim 12

The shoe insole of claim 10, wherein: said pyridinethione compound is bis[1-hydroxy-2(1H)-pyridinethionato-O,S]-(T-4)-zinc; said polyether polyol is oxypropylated glycerin; and said reaction mixture comprises water and a catalyst mixture of an amine and a stannous salt.

Claim 13

The shoe insole of claim 9, wherein said polyurethane foam is prepared by (a) placing a polyurethane foam-forming reaction mixture in a reaction zone and allowing the mixture to rise freely, thereby forming a partially cured cellular material, said reaction mixture being comprised of a polyol, an organic polyisocyanate, a foaming agent and a reaction catalyst; (b) applying a compressive force to the partially cured cellular material after completion of the rise, thereby (c) reducing the volume of the partially cured cellular material to between about 3/4 and about 1/10 of its original volume; and (d) removing the compressive force and completing the cure of the compressed cellular material.

Claim 14

The shoe insole of claim 12, wherein: said pyridinethione compound is selected from the group consisting of 2-pyridinethiol-1-oxide, sodium salt; bis[1-hydroxy-2(1H)-pyridinethionato-O,S]-(T-4)-zinc; and 2,2'-dithiobis-pyridine-1,1'-dioxide compound with magnesium sulfate (1:1); said polyether polyol is an oxypropylated polyhydric alcohol having a molecular weight of about 1,000-6,000; and said organic polyisocyanate is toluene diisocyanate.

Claim 15

The shoe insole of claim 13, wherein: said pyridinethione compound is bis[1-hydroxy-2(1H)-pyridinethionato-O,S]-(T-4)-zinc; said polyether polyol is oxypropylated glycerin; and said reaction mixture comprises water and a catalyst mixture of an amine and a stannous salt.

Claim 16

A polyurethane foam prepared from a reaction mixture comprising a polyol, an organic polyisocyanate, a foaming agent, a reaction catalyst and an effective antibacterial and antifungal proportion of a pyridinethione compound selected from the group consisting of: (a) 1-hydroxy-2(1H)-pyridinethione compounds having the formula ##STR3## wherein R represents a member of the group consisting of hydrogen, lower alkyl, lower alkoxy and halo, and n is a positive integer less than 5; and the following salts thereof: alkali metal, alkaline earth metal, aluminum, heavy metal, amine-addition and quarternary ammonium; (b) 2,2'-dithiobis-pyridine-1,1'-dioxide; and (c) adducts of 2,2'-dithiobis-pyridine-1,1'-dioxide, said adducts having the formula (C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t wherein M is an alkaline earth metal selected from the group consisting of calcium; magnesium, barium and strontium, Y is an anion selected from the group consisting of halides, sulfates, nitrates, chlorates and acetates, and t is either 1 or 2; and wherein: said polyurethane foam is compression-densified and has a density within the range from about 1.5 to about 15 pounds per cubic foot.

Claim 17

A polyurethane foam prepared from a reaction mixture comprising a polyol, an organic polyisocyanate, a foaming agent, a reaction catalyst and an effective antibacterial and antifungal proportion of a pyridinethione compound selected from the group consisting of: (a) 1-hydroxy-2(1H)-pyridinethione compounds having the formula ##STR3## wherein R represents a member of the group consisting of hydrogen, lower alkyl, lower alkoxy and halo, and n is a positive integer less than 5; and the following salts thereof: alkali metal, alkaline earth metal, aluminum, heavy metal, amine-addition and quarternary ammonium; (b) 2,2'-dithiobis-pyridine-1,1'-dioxide; and (c) adducts of 2,2'-dithiobis-pyridine-1,1'-dioxide, said adducts having the formula (C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t wherein M is an alkaline earth metal selected from the group consisting of calcium; magnesium, barium and strontium, Y is an anion selected from the group consisting of halides, sulfates, nitrates, chlorates and acetates, and t is either 1 or 2; and wherein: said polyurethane foam is compression-densified and has a density within the range from about 1.5 to about 15 pounds per cubic foot.

Claim 18

The polyurethane foam of claim 15, wherein said polyol is a polyether polyol and said reaction mixture further comprises a surfactant.

Claim 19

The polyurethane foam of claim 16, wherein said compound is employed in a proportion ranging from about 0.05 to about 0.5 parts by weight based on 100 parts by weight of total polyol.

Claim 20

The polyurethane foam of claim 16, wherein: said pyridinethione compound is selected from the group consisting of 2-pyridinethiol-1-oxide, sodium salt; bis[1-hydroxy-2(1H)-pyridinethionato-O,S]-(T-4)-zinc; and 2,2'-dithiobis-pyridine-1,1'-dioxide compound with magnesium sulfate (1:1); said polyether polyol is an oxypropylated polyhydric alcohol having a molecular weight of about 1,000-6,000; and said organic polyisocyanate is toluene diisocyanate.

Claim 21

The polyurethane foam of claim 18, wherein said pyridinethione compound is bis[1-hydroxy-2(1H)-pyridinethionato-O,S]-(T-4)-zinc; said polyether polyol is oxypropylated glycerin; and said reaction mixture comprises water and a catalyst mixture of an amine and a stannous salt.

Claim 22

The polyurethane foam of claim 16, wherein said foam is prepared by (a) placing a polyurethane foam-forming reaction mixture in a reaction zone and allowing the mixture to rise freely, thereby forming a partially cured cellular material, said reaction mixture being comprised of a polyol, an organic polyisocyanate, a foaming agent and a reaction catalyst; (b) applying a compressive force to the partially cured cellular material after completion of the rise, thereby (c) reducing the volume of the partially cured cellular material to between about 3/4 and about 1/10 of its original volume; and (d) removing the compressive force and completing the cure of the compressed cellular material.