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US4393048A Expired / Lapsed US ⏱️ 0.0 years remaining

Protective gel composition for wounds

Assignee: United States Department of the Army
•
Filing: 1981-10-30
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Granted: 1983-07-12
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Expires: 2001-10-30
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Abstract

Abstract Water soluble hydrogels of alkali metal alginate and glycerine have been found to be excellent wound dressings. The gels dry to an adherent, non-toxic pliable protective film which can be removed by water-washing when desired. The gels are also compatible with medicaments and hence can serve as vehicles or carriers for medicament application to wounds as well as a protective cover.

Inventors

  • 👤 Arthur D. Mason, Jr.
  • 👤 Avery A. Johnson, Jr.
  • 👤 Harrel L. Walker
  • 👤 Eleanor G. Bowler
  • 👤 Charles R. Ritchey

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 15:15
CPC Classifications
A; A61; A61L; A61L26/00; A61L26/0009; A61L26/0023; Y; Y10; Y10S; Y10S424/00; Y10S424/13

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 82 words
A gel composition, having use as a wound dressing, comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight of alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and which upon drying forms a flexible, stretchable, transparent water-soluble protective film, nontoxic and adherent to a wound surface to which said gel composition is applied for protection.
Claim 2
Dependent Claim 82 words
A gel composition, having use as a wound dressing, comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight of alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and which upon drying forms a flexible, stretchable, transparent water-soluble protective film, nontoxic and adherent to a wound surface to which said gel composition is applied for protection.
Claim 3
Dependent Claim 15 words
A gel composition according to claim 1 wherein the alkali metal alginate is sodium alginate.
Claim 4
Dependent Claim 22 words
A gel composition according to claim 1 further comprising a medicament dispersed therein in an amount therapeutically effective as a wound dressing.
Claim 5
Dependent Claim 13 words
A gel composition according to claim 3 wherein the medicament is silver nitrate.
Claim 6
Dependent Claim 14 words
A gel composition according to claim 3 wherein the medicament is a sulfa drug.
Claim 7
Dependent Claim 13 words
A gel composition according to claim 3 wherein the medicament is an antibiotic.
Claim 8
Dependent Claim 14 words
A gel composition according to claim 3 wherein the medicament is a chemotherapeutic agent.
Claim 9
Dependent Claim 29 words
A gel composition according to claim 3 wherein the amount of medicament is in the range of from about 0.01% to about 10% by weight of the gel composition.
Claim 10
Dependent Claim 13 words
A gel composition according to claim 5 wherein the medicament is mafenide acetate.
Claim 11
Independent Claim 83 words
A method for protecting wounds which comprises applying over a wound surface a coating of a gel composition comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and allowing the coating to dry to a water-soluble, flexible, stretchable, transparent, protective film, non-toxic and adherent to said wound surface.
Claim 12
Independent Claim 83 words
A method for protecting wounds which comprises applying over a wound surface a coating of a gel composition comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and allowing the coating to dry to a water-soluble, flexible, stretchable, transparent, protective film, non-toxic and adherent to said wound surface.
Claim 13
Dependent Claim 14 words
A method according to claim 10 wherein the alkali metal alginate is sodium alginate.
Claim 14
Dependent Claim 22 words
A method according to claim 10 wherein the gel composition comprises a medicament in an amount therapeutically effective as a wound dressing.
Claim 15
Dependent Claim 13 words
A method according to claim 10 wherein the wound is a burn wound.

References Cited (Backward Citations)

US2338416A Cited
US2405861A Cited
US2845381A Cited
US3639575A Cited
US3761590A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-07-11 1987-01-10 1987-07-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-07-11 1991-01-10 1991-07-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-07-11 1995-01-10 1995-07-12 $7700.00 Window Closed / Lapsed

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