US4386198A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2-Hydroxyaclacinomycin A and 2-hydroxyaklavinone and process for preparing same
Assignee: Mercian Corp
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Filing: 1980-09-05
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Granted: 1983-05-31
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Expires: 2000-09-05
Abstract
Abstract New anthracycline compounds, 2-hydroxyaclacinomycin A having potent antitumor activity and lower toxicity, 2-hydroxyaklavinone as an useful precursor for producing anthracycline glycosides, and a process for the production thereof by microbial conversion method are disclosed.
Inventors
- 👤 Toshikazu Oki
- 👤 Akihiro Yoshimoto
- 👤 Kageaki Kouno
- 👤 Taiji Inui
- 👤 Tomio Takeuchi
- 👤 Hamao Umezawa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 13:59
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/24; C07H15/252; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C12P; C12P19/00; C12P19/44; C12P19/56; C12P29/00; C12R; C12R2001/00; C12R2001/01; C12R2001/465; C12R2001/48
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
40 words
2-Hydroxyaklavinone and 2-hydroxyaclacinomycin A of the formula I: ##STR7## wherein R is selected from the group consisting of a hydrogen atom and a sugar residue: rhodosamine-2-deoxyfucose-cinerulose, ##STR8## and the non-toxic acid addition salts thereof when R is the sugar residue.
Claim 2
Dependent Claim
40 words
2-Hydroxyaklavinone and 2-hydroxyaclacinomycin A of the formula I: ##STR7## wherein R is selected from the group consisting of a hydrogen atom and a sugar residue: rhodosamine-2-deoxyfucose-cinerulose, ##STR8## and the non-toxic acid addition salts thereof when R is the sugar residue.
Claim 3
Dependent Claim
16 words
The compound of claim 1, wherein R is rhodosamine-2-deoxyfucose-cinerulose and the non-toxic, acid addition salts thereof.
Claim 4
Dependent Claim
13 words
A compound of the formula I of claim 1 wherein R is hydrogen.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-05-30 | 1986-11-29 | 1987-05-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-05-30 | 1990-11-29 | 1991-05-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-05-30 | 1994-11-29 | 1995-05-31 | $7700.00 | Window Closed / Lapsed |