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US4382946A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of alleviating withdrawal symptoms

Assignee: BRITANNA PHARMACEUTICALS Ltd
•
Filing: 1981-12-14
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Granted: 1983-05-10
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Expires: 2001-12-14
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Abstract

Abstract The use of lofexidine and its pharmaceutically acceptable salts in alleviating the adverse symptoms of drug withdrawal is disclosed.

Inventors

  • 👤 Albert Sjoerdsma

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 20:33
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/415

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 46 words
A method of alleviating the adverse symptoms of withdrawal from a drug substance selected from the group consisting of alcohol and methadone, which comprises administering an anti-withdrawal effective amount of lofexidine or a pharmaceutical salt thereof to an individual dependent upon said drug or drug substance.
Claim 2
Independent Claim 46 words
A method of alleviating the adverse symptoms of withdrawal from a drug substance selected from the group consisting of alcohol and methadone, which comprises administering an anti-withdrawal effective amount of lofexidine or a pharmaceutical salt thereof to an individual dependent upon said drug or drug substance.
Claim 3
Dependent Claim 17 words
A method according to claim 1 wherein the dosage is from 0.1 to 1.6 milligrams per day.
Claim 4
Dependent Claim 11 words
A method according to claim 1 wherein the drug is alcohol.
Claim 5
Dependent Claim 11 words
A method according to claim 1 wherein the drug is methadone.

References Cited (Backward Citations)

US4312878A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-05-09 1986-11-08 1987-05-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-05-09 1990-11-08 1991-05-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-05-09 1994-11-08 1995-05-10 $7700.00 Window Closed / Lapsed

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