US4379930A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Preparation of 2-t-butyl-5-hydroxypyrimidine
Assignee: Dow Chemical Co
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Filing: 1981-09-14
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Granted: 1983-04-12
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Expires: 2001-09-14
Abstract
Abstract The hydrolysis of 2-t-butyl-5-halopyrimidines is carried out in the presence of an alkali metal methoxide and a catalytic amount of an N-oxide, a disulfide or elemental sulfur to prepare 2-t-butyl-5-hydroxypyrimidine in good yields and purity.
Inventors
- 👤 Richard G. Pews
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 11:33
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/32; C07D239/34; C07D239/36
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
27 words
A method of making 2-t-butyl-5-hydroxypyrimidine which comprises hydrolyzing a 2-t-butyl-5-halopyrimidine in the presence of an alkali metal methoxide and a catalyst comprising 2-picoline-n-oxide, di-n-butyldisulfide or elemental sulfur.
Claim 2
Independent Claim
27 words
A method of making 2-t-butyl-5-hydroxypyrimidine which comprises hydrolyzing a 2-t-butyl-5-halopyrimidine in the presence of an alkali metal methoxide and a catalyst comprising 2-picoline-n-oxide, di-n-butyldisulfide or elemental sulfur.
Claim 3
Dependent Claim
9 words
Method of claim 1 wherein the halopyrimidine is 2-t-butyl-5-bromopyrimidine.
Claim 4
Dependent Claim
9 words
Method of claim 1 wherein the halopyrimidine is 2-t-butyl-5-chloropyrimidine.
Claim 5
Dependent Claim
15 words
Method of claim 2 wherein the reaction is carried out at 150° to 220° C.
References Cited (Backward Citations)
US3907797A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-04-11 | 1986-10-11 | 1987-04-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-04-11 | 1990-10-11 | 1991-04-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-04-11 | 1994-10-11 | 1995-04-12 | $7700.00 | Window Closed / Lapsed |