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US4377697A Expired / Lapsed US ⏱️ 0.0 years remaining

Imidazole hydrazone and hydrazine derivatives

Assignee: GD Searle LLC
•
Filing: 1982-02-02
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Granted: 1983-03-22
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Expires: 2002-02-02
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Abstract

Abstract Compounds of the general formulae: ##STR1## in which Ar and Ar 1 which may be the same or different represent aromatic radicals optionally substituted once or more than by substituents selected from halogen, lower alkyl and lower alkoxy and Alk represents an alkylene group containing from 1 to 4 carbon atoms which alkylene group may be interrupted with a heteroatom; and acid addition salts thereof. These compounds have anti-anaerobe and also anti-fungal activity and are non-mutagenic.

Inventors

  • 👤 Peter J. Fellner
  • 👤 George Ellames
  • 👤 Christopher D. Floyd
  • 👤 Paul W. Manley

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 21:27
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/02; C07D231/10; C07D231/12; A; A61; A61P; A61P31/00; A61P31/04; C07D233/00; C07D233/54; C07D233/56; C07D249/00; C07D249/02; C07D249/08

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 65 words
Compounds of the general formulae: ##STR6## in which Ar and Ar 1 which may be the same or different, represent aromatic radicals optionally substituted once or more than by substituents selected from halogen, lower alkyl and lower alkoxy and Alk represents an alkylene group containing from 1 to 4 carbon atoms which alkylene group may be interrupted with a heteroatom; and acid addition salts thereof.
Claim 2
Dependent Claim 65 words
Compounds of the general formulae: ##STR6## in which Ar and Ar 1 which may be the same or different, represent aromatic radicals optionally substituted once or more than by substituents selected from halogen, lower alkyl and lower alkoxy and Alk represents an alkylene group containing from 1 to 4 carbon atoms which alkylene group may be interrupted with a heteroatom; and acid addition salts thereof.
Claim 3
Dependent Claim 23 words
Compounds as claimed in claim 1 in which Ar represents a phenyl group or a thienyl group optionally substituted with one halogen atom.
Claim 4
Dependent Claim 15 words
Compounds as claimed in claim 2 in which the halogen atom is a chlorine atom.
Claim 5
Dependent Claim 23 words
Compounds as claimed in any of claims 1 to 3 in which Alk is an alkyl group containing 3 or 4 carbon atoms.
Claim 6
Dependent Claim 11 words
A compound as claimed in claim 1 which is 2-chloro-6-(1H-imidazol-1-yl)-6,7,8,9-tetrahydro-5-benzocycloheptanone, 2,4-dichlorophenylhydrazone.
Claim 7
Dependent Claim 11 words
A compound as claimed in claim 1 which is 6-(1H-imidazol-1-yl)-6,7,8,9-tetrahydro-5-benzocycloheptanone, 2,4-dichlorophenylhydrazone.
Claim 8
Dependent Claim 11 words
A compound as claimed in claim 1 which is 2-chloro-6-(1H-imidazol-1-yl)-6,7,8,9-tetrahydro-5-benzocycloheptanone, 2,4,6-trichlorophenylhydrazone.
Claim 9
Dependent Claim 11 words
A compound as claimed in claim 1 which is 6-(1H-imidazol-1-yl)-7,8,9,10-tetrahydro-5(6H)-benzocyclooctanone, 2,4-dichlorophenylhydrazone.
Claim 10
Dependent Claim 11 words
A compound as claimed in claim 1 which is 7-(1H-imidazol-1-yl)-4,5,6,7-tetrahydro-8H-cyclohepta[b]-thiophen-8-one, 2,4-dichlorophenylhydrazone.
Claim 11
Dependent Claim 11 words
A compound as claimed in claim 1 which is 6-(1H-imidazol-1-yl)-7,8,9,10-tetrahydro-5(6H)-benzocyclooctanone, 2,4,6-trichlorophenylhydrazone.

References Cited (Backward Citations)

US3621027A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-03-21 1986-09-20 1987-03-22 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-03-21 1990-09-20 1991-03-22 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-03-21 1994-09-20 1995-03-22 $7700.00 Window Closed / Lapsed

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