Denture fixative composition

Claim 1

A denture fixative composition comprising a dentally acceptable excipient and an effective fixative amount of a fixative mixture comprising hydroxypropylcellulose and (a) polyacrylic acid partially neutralized by at least one dentally acceptable monovalent cation such that about 20-90% of the initial carboxy groups have been neutralized and 0-80% of the initial carboxy groups have been crosslinked by at least one dentally acceptable agent selected from the group consisting of divalent cations and polyhydroxy compounds, wherein a 1% aqueous solution of said polyacrylic acid has a pH of at least about 4.5, or a precursor combination of polyacrylic acid, neutralizing agent and crosslinking agent adapted to form said polyacrylic acid in an aqueous environment; (b) partially neutralized lower alkyl vinyl ether-maleic acid or anhydride copolymer, which has been partially neutralized by at least one dentally acceptable monovalent cation and 0-50% of the initial carboxy groups have been crosslinked by at least one dentally acceptable agent selected from the group consisting of divalent cations and polyhydroxy compounds such that up to about 90% of the total number of initial carboxyl groups have been neutralized or crosslinked, wherein a 1% aqueous solution of said neutralized copolymer has a pH of at least about 4.5, or a precursor combination of said copolymer, neutralizing agent and crosslinking agent adapted to form said partially neutralized copolymer in aqueous environment; (c) polyethylene oxide; or (d) a combination of (c) with (a) or (b).