US4372957A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment with dialkoxy pyridopyrimidines
Assignee: SmithKline Beecham Corp
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Filing: 1981-01-23
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Granted: 1983-02-08
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Expires: 2001-01-23
Abstract
Abstract Potent psoriasis activity in combination with low inhibition of histamine N-methyltransferase has been found in a class of 2,4-diamino-6-(2,5-dialkoxybenzyl)-5-methylpyrido[2,3-d]pyrimidines.
Inventors
- 👤 David S. Duch
- 👤 Charles A. Nichol
- 👤 Carl W. Sigel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 04:12
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/04; A; A61; A61P; A61P17/00; A61P35/00; A61P43/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
50 words
A method of treating psoriasis in a mammal suffering from psoriasis comprising the administration to said mammal of a non-toxic, effective antipsoriasis amount of a compound of formula (II): ##STR25## wherein R and R' are lower (C 1 -C 6 ) alkyl, or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Independent Claim
50 words
A method of treating psoriasis in a mammal suffering from psoriasis comprising the administration to said mammal of a non-toxic, effective antipsoriasis amount of a compound of formula (II): ##STR25## wherein R and R' are lower (C 1 -C 6 ) alkyl, or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Independent Claim
25 words
A method of treating psoriasis in a mammal suffering from psoriasis comprising the administration to said mammal of a non-toxic, effective antipsoriasis amount of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine.
Claim 4
Independent Claim
25 words
A method of treating psoriasis in a mammal suffering from psoriasis comprising the administration to said mammal of a non-toxic, effective antipsoriasis amount of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine.
Claim 5
Dependent Claim
20 words
The method of claim 1 or 2 in which the compound or salt is administered in a pharmaceutically acceptable carrier.
Claim 6
Dependent Claim
22 words
The method of claim 1 or 2 in which the compound or salt is administered as a part of a topical formulation.
Claim 7
Dependent Claim
37 words
The method of claim 1 or 2 in which the compound or salt is administered as a part of a topical formulation in which the compound or salt is at a concentration of 0.05 to 2% w/w.
Claim 8
Dependent Claim
24 words
The method of claim 1 or 2 in which the compound or salt is administered as part of an oral preparation or parenteral preparation.
Claim 9
Independent Claim
16 words
The method of claims 1 or 2 in which the compound or salt is topically administered.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-02-07 | 1986-08-09 | 1987-02-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-02-07 | 1990-08-09 | 1991-02-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-02-07 | 1994-08-09 | 1995-02-08 | $7700.00 | Window Closed / Lapsed |