US4372949A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of cancer with carcinostatic and immunostimulating agent containing lysophospholipid and phospholipid
Assignee: Toyama Chemical Co Ltd
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Filing: 1980-02-29
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Granted: 1983-02-08
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Expires: 2000-02-29
Abstract
Abstract A carcinostatic and immunostimulating agent containing a lysophospholipid and a phospholipid. Said carcinostatic and immunostimulating agent is useful for the treatment of cancerous diseases of the mammals including human being. This disclosure concerns such a carcinostatic and immunostimulating agent and a process for preparing the same as well as a method for treating the cancerous diseases by using said agent.
Inventors
- 👤 Yutaka Kodama
- 👤 Kaoru Oyama
- 👤 Ryusaku Shimizu
- 👤 Masao Nakabayashi
- 👤 Yoshifumi Nakashima
- 👤 Takashi Sano
- 👤 Masaaki Shibata
- 👤 Kiyoshi Goden
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A61K31/683; A61K31/685
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
47 words
A method for treating a host mammal having cancer, which comprises administering to said host mammal a therapeutically effective amount of a composition comprising a lysophospholipid and a phospholipid in an amount of 1 part by weight of lysophospholidpid to from 1.0-500 parts by weight of phospholipid.
Claim 2
Independent Claim
47 words
A method for treating a host mammal having cancer, which comprises administering to said host mammal a therapeutically effective amount of a composition comprising a lysophospholipid and a phospholipid in an amount of 1 part by weight of lysophospholidpid to from 1.0-500 parts by weight of phospholipid.
Claim 3
Dependent Claim
16 words
The method according to claim 1, wherein the composition is in the form of lipid vesicles.
Claim 4
Dependent Claim
19 words
The method according to claim 2, wherein the lipid vesicles have a particle size of not more than 1.0μ.
Claim 5
Independent Claim
70 words
The method according to claims 1, 2 or 3 wherein the lysophospholipid is a compound of the formula: ##STR2## wherein R 1 is a C 5 -C 22 acyloxy or C 5 -C 22 alkoxy group, R 2 is hydrogen, hydroxyl, C 1-5 acyloxy, or C 1-5 alkoxy group, and R 3 is hydrogen or C 1-5 alkyl group, said R 1 and R 2 being interchangeable with each other.
Claim 6
Independent Claim
14 words
The method according to claims 1, 2 or 3 wherein the lysophospholipid is lysolecithin.
Claim 7
Independent Claim
18 words
The method according to claims 2 or 3 wherein the lysophospholipid is lysolecithin and the phospholipid is lecithin.
Claim 8
Dependent Claim
22 words
The method of claim 1 wherein there is 1 part by weight of lysophospholipid to from 5-20 parts by weight of phospholipid.
Claim 9
Independent Claim
48 words
A method for treating a mammal having cancer, which comprises administering to said mammal a composition comprising a lysophospholipid and a phospholipid wherein the phospholipid is in the form of a fat emulsion, and there is from 0.1 to 50 mg lysophospholipid per 1 ml of fat emulsion.
Claim 10
Independent Claim
48 words
A method for treating a mammal having cancer, which comprises administering to said mammal a composition comprising a lysophospholipid and a phospholipid wherein the phospholipid is in the form of a fat emulsion, and there is from 0.1 to 50 mg lysophospholipid per 1 ml of fat emulsion.
Claim 11
Dependent Claim
24 words
The method of claim 8 wherein the lysophospholipid is in amount of from 1 to 10 mg per 1 ml of the fat emulsion.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-02-07 | 1986-08-09 | 1987-02-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-02-07 | 1990-08-09 | 1991-02-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-02-07 | 1994-08-09 | 1995-02-08 | $7700.00 | Window Closed / Lapsed |