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US4369319A
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10-Alkyl-10-deazaminopterins
Assignee: Individual
•
Filing: 1981-02-10
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Granted: 1983-01-18
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Expires: 2001-02-10
Abstract
Abstract A process and composition are provided employing 10-deazaminopterin and 10-alkyl derivatives thereof for the treatment of leukemia, as well as other tumor systems including those of ascitic character, and also a process for preparing 10-deazaminopterin compounds.
Inventors
- 👤 Joseph I. DeGraw, Jr.
- 👤 Francis M. Sirotnak
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 20:31
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61K9/02; A61P; A61P35/00; A61P35/02; C; C07; C07D; C07D475/00; C07D475/06; C07D475/08
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
43 words
10-Deazaminopterin compounds having the formula: ##STR6## wherein: R 1 and R 2 are both selected from the group consisting of hydrogen and alkyl having from one to about eight carbon atoms, and at least one of R 1 and R 2 is alkyl.
Claim 2
Dependent Claim
43 words
10-Deazaminopterin compounds having the formula: ##STR6## wherein: R 1 and R 2 are both selected from the group consisting of hydrogen and alkyl having from one to about eight carbon atoms, and at least one of R 1 and R 2 is alkyl.
Claim 3
Dependent Claim
22 words
10-Deazaminopterin compounds according to claim 1 in which one of R 1 and R 2 is alkyl and the other is hydrogen.
Claim 4
Dependent Claim
12 words
10-Deazaminopterin compounds according to claim 2 in which the alkyl is ethyl.
Claim 5
Dependent Claim
12 words
10-Deazaminopterin compounds according to claim 2 in which the alkyl is methyl.
Claim 6
Dependent Claim
17 words
10-Deazaminopterin compounds according to claim 1 in which both of R 1 and R 2 are alkyl.
Claim 7
Dependent Claim
12 words
10-Deazaminopterin compounds according to claim 5 in which the alkyl is methyl.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-01-17 | 1986-07-19 | 1987-01-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-01-17 | 1990-07-19 | 1991-01-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-01-17 | 1994-07-19 | 1995-01-18 | $7700.00 | Window Closed / Lapsed |