US4365632A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for inducing immunological and resistant response in mammary glands
Assignee: KORTUM Inc 180 ELY ROAD PETALUMA CALIFORNIA 94952 A CA CORP
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Filing: 1979-12-12
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Granted: 1982-12-28
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Expires: 1999-12-12
Abstract
Abstract Process and apparatus are provided for stimulating immune resistance by the introduction of at least one relatively small solid non-toxic substantially non-biodegradable body, having non-specific antigenic action, into each gland cistern of the udder. The body is sufficiently flexible or elastic and of a shape so as to be capable of being shaped into a form small enough to be inserted into the gland cistern through the lactiferous duct and then reformed to its original shape which inhibits its passage from the gland cistern into the teat cistern. The continued presence of the non-specific antigenic body induces immune resistance including an increase in the number and activity of phagocytic cells, particularly leukocyte cells, in the udder. The continued presence of these increased numbers of activated phagocytic cells provides protection against bacterial invasion through the streak canal without degrading milk quality.
Inventors
- 👤 William M. Kortum
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 18:19
CPC Classifications
A; A61; A61D; A61D1/00; A61D1/02; A61D7/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
143 words
A kit inhibiting bacterial infection in an udder of a milk-producing domestic animal comprising: a plastic non-toxic antigenic device comprising an elongate cylinder having at least one end tapered so that said end may be inserted into the udder through the teat sphincter and be retained in the gland cistern; means comprising a straight hollow tube for introducing said device into the udder; and means comprising a rod disposed within said tube for inserting said device into the gland cistern; said device having an appendage capable of being drawn into said tube; and said inserting means having at one end of said rod a clasp means for attaching to said device appendage, said clasp means being operative to hold said device appendage whenever said one end is within said tube and to release said device appendage whenever one end is external said tube.
Claim 2
Dependent Claim
143 words
A kit inhibiting bacterial infection in an udder of a milk-producing domestic animal comprising: a plastic non-toxic antigenic device comprising an elongate cylinder having at least one end tapered so that said end may be inserted into the udder through the teat sphincter and be retained in the gland cistern; means comprising a straight hollow tube for introducing said device into the udder; and means comprising a rod disposed within said tube for inserting said device into the gland cistern; said device having an appendage capable of being drawn into said tube; and said inserting means having at one end of said rod a clasp means for attaching to said device appendage, said clasp means being operative to hold said device appendage whenever said one end is within said tube and to release said device appendage whenever one end is external said tube.
Claim 3
Dependent Claim
42 words
A kit according to claim 1 wherein said elongate cylinder assumes an unstraightened shape when in an unstressed state and wherein at least a portion of said cylinder is capable of being drawn in straightened form into said tube by said rod.
Claim 4
Dependent Claim
90 words
A kit according to claim 2 wherein said device includes a clasp means for mating with said rod clasp means, said device clasp means being located at the end of the cylinder opposite to the tapered end and wherein said device clasp means is capable of being separated from said rod clasp means only by lateral movement and wherein said tube is of a sufficiently small inner diameter to prevent clasp separation by lateral movement whenever said rod clasp means and said device clasp means are mated within said tube.
Claim 5
Dependent Claim
50 words
A kit according to claim 3 wherein the tapered end of the elongate cylinder comprises a blunted point having a shoulder which limits the extent which the device can be drawn into said tube and wherein said tube and said blunted point cooperate for introducing said device into the udder.
Claim 6
Dependent Claim
16 words
A kit according to claim 4 wherein said device in an unstressed state is a coil.
Claim 7
Dependent Claim
16 words
A kit according to claim 4 wherein said device in an unstressed state is a spiral.
Claim 8
Dependent Claim
31 words
A kit according to claim 4 further including an aseptic container of sufficient size to enclose said device in its unstraightened state together with said inserting means and said introducing means.
Claim 9
Independent Claim
114 words
A system comprising an antigenic device and an apparatus for inserting said device through a teat sphincter and into the udder of a domestic milk-producing animal, wherein: (a) the antigenic device is a nonlinear resilient tube capable of being substantially straightened and having a clasp at one end and a means for penetrating the teat sphincter at the other end; and (b) the apparatus includes: a hollow tube having an internal diameter substantially equal to the diameter of the tube but insufficient to allow entry of the means for penetrating; and means for engaging the clasp and drawing the device into the tube until only the means for penetrating projects out of the tube.
Claim 10
Independent Claim
114 words
A system comprising an antigenic device and an apparatus for inserting said device through a teat sphincter and into the udder of a domestic milk-producing animal, wherein: (a) the antigenic device is a nonlinear resilient tube capable of being substantially straightened and having a clasp at one end and a means for penetrating the teat sphincter at the other end; and (b) the apparatus includes: a hollow tube having an internal diameter substantially equal to the diameter of the tube but insufficient to allow entry of the means for penetrating; and means for engaging the clasp and drawing the device into the tube until only the means for penetrating projects out of the tube.
Claim 11
Dependent Claim
36 words
A system as in claim 8, wherein the means for penetrating is a blunt conical tip having a shoulder which projects radially outward from the tube and prevents the tip from being drawn into the tube.
Claim 12
Dependent Claim
23 words
A system as in claim 8, wherein the maximum cross-sectional dimension of the device is in the range from 0.1 to 0.8 cm.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-12-27 | 1986-06-28 | 1986-12-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-12-27 | 1990-06-28 | 1990-12-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-12-27 | 1994-06-28 | 1994-12-28 | $7700.00 | Window Closed / Lapsed |