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US4363801A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for treating hyperbilirubinemia

Assignee: Texas A&M University System
•
Filing: 1981-02-09
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Granted: 1982-12-14
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Expires: 2001-02-09
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Abstract

Abstract Methods and preparations for treating hyperbilirubinemia utilizing chitosan salts as the active agent. A method of preparing the chitosan salts for oral administration in a liquid carrier is disclosed.

Inventors

  • 👤 Joseph J. Nagyvary

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 00:28
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61K31/716; A61K31/722; A61K9/00; A61K9/0087; A61K9/0095; A61K9/14; A61K9/19

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 29 words
A method of treating hyperbilirubinemia which comprises orally administering to the affected patient an amount of soluble chitosan effective to substantially reduce the amount of bilirubin in the blood.
Claim 2
Independent Claim 29 words
A method of treating hyperbilirubinemia which comprises orally administering to the affected patient an amount of soluble chitosan effective to substantially reduce the amount of bilirubin in the blood.
Claim 3
Dependent Claim 24 words
The method of claim 1 in which said chitosan is administered as a water soluble salt in a solution of water with flavor additives.
Claim 4
Dependent Claim 21 words
The method of claim 1 in which said chitosan is administered as a chitosan salt in a solution of fruit juice.
Claim 5
Dependent Claim 25 words
The method of claim 3 in which the amount of chitosan salt administered is from 0.5 to 5 grams per 200 ml of fruit juices.
Claim 6
Dependent Claim 23 words
The method of claim 1 in which said chitosan is administered in an amount of from 1% to 12% of the patient's diet.
Claim 7
Dependent Claim 49 words
The method as set forth in claim 2 in which said chitosan salt is formed by: dissolving chitosan in a weak acidic solution; agitating said solution; lyophilizing said solution; and pulverizing the chitosan salts from said lyophilizing into a finely ground powder for mixing in said solution of water.
Claim 8
Dependent Claim 51 words
The method as set forth in claim 3 in which said chitosan salt is formed by: dissolving chitosan in a weak acidic solution; agitating said solution; lyophilizing said solution; and pulverizing the chitosan salts from said lyophilizing into a finely ground powder for said mixing in said solution of fruit juice.

References Cited (Backward Citations)

US2040879A Cited
US3155575A Cited
US3879376A Cited
US4223023A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-12-13 1986-06-14 1986-12-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-12-13 1990-06-14 1990-12-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-12-13 1994-06-14 1994-12-14 $7700.00 Window Closed / Lapsed

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