US4361564A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Renoprotective treatments employing vasodilator compounds
Assignee: Individual
•
Filing: 1981-02-09
•
Granted: 1982-11-30
•
Expires: 2001-02-09
Abstract
Abstract A treatment method and substances have been found to reduce the risk of incurring renal damage or failure. Vasodilators useful for the treatment of hypertension have been found to lower cholesterol levels and prevent renal failure or damage. These substances are administered alone or in combination with other substances useful in the treatment of hyperlipidemia such as phenoxyacetic acid derivatives.
Inventors
- 👤 K. David G. Edwards
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 06:26
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/21; A61K31/215; A61K31/22; A61K31/185; A61K31/19
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
65 words
A method of treating renal damage or failure in a host in need of treatment comprising administering to said host an effective amount for treating renal damage or failure; a vasodilator having postsynaptic alpha-adrenoceptor blocking activity and having antihyperlipidemic characteristics which lower the lipid levels in the bloodstream of the host, the vasodilator being selected from a group consisting of hydralazine hydrochloride and prazosin hydrochloride.
Claim 2
Independent Claim
65 words
A method of treating renal damage or failure in a host in need of treatment comprising administering to said host an effective amount for treating renal damage or failure; a vasodilator having postsynaptic alpha-adrenoceptor blocking activity and having antihyperlipidemic characteristics which lower the lipid levels in the bloodstream of the host, the vasodilator being selected from a group consisting of hydralazine hydrochloride and prazosin hydrochloride.
Claim 3
Dependent Claim
40 words
A method of treating renal damage or failure in accordance with claim 1 wherein the vasodilator is hydralazine hydrochloride and the hydralazine hydrochloride is administered to the host in substantially daily quantities totalling approximately from 40 milligrams through 200 milligrams.
Claim 4
Dependent Claim
40 words
A method of treating renal damage or failure in accordance with claim 1 wherein the vasodilator is prazosin hydrochloride and the prazosin hydrochloride is administered to the host in substantially daily quantities totalling approximately from 1 milligram through 40 milligrams.
Claim 5
Dependent Claim
34 words
A method of treating renal damage or failure in accordance with claim 1 wherein the clonidine hydrochloride is administered to the host in substantially daily quantities totalling approximately from 0.1 milligram through 2.4 milligrams.
Claim 6
Dependent Claim
39 words
A method of treating renal damage or failure in accordance with claim 1 including administering to the host an effective amount for treating renal damage or failure of a further substance having antihyperlipidemic characteristics comprising a phenoxyacetic acid derivative.
Claim 7
Independent Claim
57 words
A method of treating renal damage or failure in a host in need of treatment comprising administering to said host an effective amount for treating renal damage or failure a vasodilator having central alpha-adrenergic receptor binding activity and having antihyperlipidemic characteristics which lower the lipid levels in the bloodstream of the host, said vasodilator is clonidine hydrochloride.
Claim 8
Independent Claim
57 words
A method of treating renal damage or failure in a host in need of treatment comprising administering to said host an effective amount for treating renal damage or failure a vasodilator having central alpha-adrenergic receptor binding activity and having antihyperlipidemic characteristics which lower the lipid levels in the bloodstream of the host, said vasodilator is clonidine hydrochloride.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-11-29 | 1986-05-31 | 1986-11-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-11-29 | 1990-05-31 | 1990-11-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-11-29 | 1994-05-31 | 1994-11-30 | $7700.00 | Window Closed / Lapsed |