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US4358376A Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus for detoxifying body fluid

Assignee: Terumo Corp
•
Filing: 1980-10-27
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Granted: 1982-11-09
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Expires: 2000-10-27
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Abstract

Abstract An apparatus for detoxifying body fluid has a columnar hollow container with an inlet and an outlet for body fluid. This container is filled with non-coated petroleum pitch activated carbon particles which have been washed by ultrasonic waves to a degree that the number of carbon dust fine particles released in a physiologically acceptable solution is less than 100 particles/ml for particles of more than 2μ diameter and less than 10 particles/ml for particles of more than 5μ diameter.

Inventors

  • 👤 Yousuke Moriuchi
  • 👤 Atsushi Shimizu

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 00:47
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/36; A61M1/3679

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 117 words
An apparatus for detoxifying a body fluid comprising: a columnar hollow container having an inlet and an outlet for body fluid; and a plurality of noncoated petroleum pitch activated carbon particles; said container being filled with (i) said particles and (ii) a physiologically acceptable filling liquid containing between 50 and 5,000 units of heparin per gram of said activated carbon particles; and said activated carbon particles having been washed in a physiologically acceptable cleaning solution with ultrasonic waves until the number of carbon dust fine particles released in the cleaning solution is less than 100 particles/ml for particles of more than 2μ particle size and less than 10 particles/ml for particles of more than 5μ particle size.
Claim 2
Independent Claim 117 words
An apparatus for detoxifying a body fluid comprising: a columnar hollow container having an inlet and an outlet for body fluid; and a plurality of noncoated petroleum pitch activated carbon particles; said container being filled with (i) said particles and (ii) a physiologically acceptable filling liquid containing between 50 and 5,000 units of heparin per gram of said activated carbon particles; and said activated carbon particles having been washed in a physiologically acceptable cleaning solution with ultrasonic waves until the number of carbon dust fine particles released in the cleaning solution is less than 100 particles/ml for particles of more than 2μ particle size and less than 10 particles/ml for particles of more than 5μ particle size.
Claim 3
Dependent Claim 32 words
An apparatus according to claim 1, wherein filtering materials having pores small enough to support the activated carbon particles are disposed at the inlet side and the outlet side of the container.
Claim 4
Dependent Claim 19 words
An apparatus according to claim 2, wherein the activated carbon has a particle diameter of 0.1 to 1 mm.
Claim 5
Dependent Claim 17 words
An apparatus according to claim 2, wherein the filtering materials have pores of 200 to 250μ diameter.
Claim 6
Dependent Claim 17 words
An apparatus according to claim 4, wherein the container has a capacity of 50 to 600 cc.
Claim 7
Dependent Claim 19 words
An apparatus according to claim 5, wherein said activated carbon particles are filled in the container to maximum density.
Claim 8
Dependent Claim 22 words
An apparatus according to claim 1, wherein the filling liquid is water, a physiological saline solution or an aqueous solution of dextran.
Claim 9
Independent Claim 212 words
An apparatus for detoxifying a body fluid comprising a hollow container having an inlet and an outlet for body fluid, noncoated petroleum pitch activated carbon particles filled in the container together with a physiologically acceptable filling liquid containing between 50 and 5,000 units of heparin per gram of said activated carbon particles; and filtering materials disposed at the inlet side and the outlet side of the container to support the activated carbon particles within the container, the apparatus being obtained by (a) washing the activated carbon particles in a physiologically acceptable cleaning solution by means of ultrasonic waves; (b) during the washing, removing carbon dust fine particles released in the cleaning solution from the activated carbon particles until the number of carbon dust fine particles in the cleaning solution is less than 100 particles/ml for particles of more than 2μ particles size and less than 10 particles/ml for particles of more than 5μ particle size, with or without the circulation of the cleaning solution; (c) filling the thus washed carbon particles in the container together with the filling liquid comprising the cleaning solution or a substitute liquid therefore, (d) supporting the filled carbon particles by the filtering materials, (e) sealing the inlet and outlet, and (f) sterilizing the apparatus in an autoclave.
Claim 10
Independent Claim 212 words
An apparatus for detoxifying a body fluid comprising a hollow container having an inlet and an outlet for body fluid, noncoated petroleum pitch activated carbon particles filled in the container together with a physiologically acceptable filling liquid containing between 50 and 5,000 units of heparin per gram of said activated carbon particles; and filtering materials disposed at the inlet side and the outlet side of the container to support the activated carbon particles within the container, the apparatus being obtained by (a) washing the activated carbon particles in a physiologically acceptable cleaning solution by means of ultrasonic waves; (b) during the washing, removing carbon dust fine particles released in the cleaning solution from the activated carbon particles until the number of carbon dust fine particles in the cleaning solution is less than 100 particles/ml for particles of more than 2μ particles size and less than 10 particles/ml for particles of more than 5μ particle size, with or without the circulation of the cleaning solution; (c) filling the thus washed carbon particles in the container together with the filling liquid comprising the cleaning solution or a substitute liquid therefore, (d) supporting the filled carbon particles by the filtering materials, (e) sealing the inlet and outlet, and (f) sterilizing the apparatus in an autoclave.
Claim 11
Dependent Claim 21 words
An apparatus according to claim 8, wherein the filling liquid is water, a physiological saline solution or an aqueous dextran solution.

References Cited (Backward Citations)

US3725113A Cited
US3770625A Cited
US3888250A Cited
US4169051A Cited
US4250141A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-11-08 1986-05-10 1986-11-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-11-08 1990-05-10 1990-11-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-11-08 1994-05-10 1994-11-09 $7700.00 Window Closed / Lapsed

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