US4352813A
Expired / Lapsed
US
⏱️ 0.0 years remaining
[(1-Benzyl-1H-indazol-3-yl)oxy] acetic acid salt with L. lysine
Assignee: Angelini Acraf SpA
•
Filing: 1981-06-02
•
Granted: 1982-10-05
•
Expires: 2001-06-02
Abstract
Abstract A new salt of [(1-benzyl-1H-indazol-3-yl)oxy] acetic acid (or bendazac) with L. lysine. Following oral administrations of this compound in man, the concentrations of bendazac found in the blood are higher than those obtained after administration of bendazac as such. This discovery extends the therapeutic use of bendazac. In fact, whereas up to now bendazac could only be used topically, the L. lysine salt of bendazac makes it possible to perform therapeutic treatments with the oral route of administration as an agent with a normalizing effect on blood lipids.
Inventors
- 👤 Bruno Silvestrini
- 👤 Leandro Baiocchi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 05:30
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/54; C07D231/56; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/415; A61P; A61P29/00; A61P3/00; A61P3/06
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
9 words
A salt of [(1-benzyl-1H-indazol-3-yl)oxy] acetic acid with L. lysine.
Claim 2
Dependent Claim
9 words
A salt of [(1-benzyl-1H-indazol-3-yl)oxy] acetic acid with L. lysine.
Claim 3
Dependent Claim
32 words
A pharmaceutical composition for use in the treatment of high blood lipids levels comprising an amount of the compound of claim 1 effective in said treatment together with a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
35 words
A method for the treatment of humans suffering from high blood lipid levels comprising orally administering to said human being an amount of the compound of claim 1 effective to decrease high blood lipid levels.
References Cited (Backward Citations)
FR1530097A
Cited
US3470194A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-10-04 | 1986-04-05 | 1986-10-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-10-04 | 1990-04-05 | 1990-10-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-10-04 | 1994-04-05 | 1994-10-05 | $7700.00 | Window Closed / Lapsed |