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US4350707A Expired / Lapsed US ⏱️ 0.0 years remaining

Inactivation of lipid containing viruses with butylated hydroxytoluene

Assignee: Research Corp
•
Filing: 1976-02-05
•
Granted: 1982-09-21
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Expires: 1996-02-05
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Abstract

Abstract Inactivation of, and treatment of diseases caused by, lipid containing viruses, particularly herpes simplex virus, with butylated hydroxytoluene.

Inventors

  • 👤 Alec D. Keith
  • 👤 Wallace Snipes

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 09:41
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/045; A61K31/05; Y; Y02; Y02A; Y02A50/00; Y02A50/30

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 32 words
A method for treating a subject having a disease caused by lipid-containing viruses comprising administering to said subject an effective inactivating amount therefor of butylated hydroxytoluene in a non-toxic, pharmaceutically acceptable barrier.
Claim 2
Independent Claim 32 words
A method for treating a subject having a disease caused by lipid-containing viruses comprising administering to said subject an effective inactivating amount therefor of butylated hydroxytoluene in a non-toxic, pharmaceutically acceptable barrier.
Claim 3
Dependent Claim 20 words
A method according to claim 1, wherein the concentration of said butylated hydroxytoluene in said carrier is 1% to saturation.
Claim 4
Dependent Claim 14 words
A method according to claim 2, wherein said pharmaceutically acceptable carrier is mineral oil.
Claim 5
Dependent Claim 36 words
A method according to claim 2, wherein said pharmaceutically acceptable carrier is 40 to 60% ethanol, 30 to 45% propylene glycol, 0 to 5% water, and 0 to 8% monolaurate ethoxylated (20 units/mole) ester of sorbitan.
Claim 6
Dependent Claim 24 words
A method according to claim 2, wherein the affected area is skin, eyes and mucocutaneous areas including lips, nares, prepuce, glans penis and cervix.
Claim 7
Dependent Claim 19 words
A method according to claim 5, wherein the affected skin area is the hands, face, neck or external genitalia.
Claim 8
Dependent Claim 14 words
A method according to claim 2, wherein said virus is a herpes simplex virus.
Claim 9
Dependent Claim 25 words
A method according to claim 7, wherein said disease is an eye disease caused by herpes simplex and the butylated hydroxytoluene is applied topically thereto.
Claim 10
Dependent Claim 30 words
The method according to claim 7, wherein said disease is a topical infection caused by herpes simplex in man and the butylated hydroxytoluene is applied topically to the infected areas.
Claim 11
Independent Claim 24 words
A method for inactivating lipid-containing viruses comprising exposing said viruses to an effective inactivating amount of butylated hydroxytoluene in a non-toxic pharmaceutically acceptable carrier.
Claim 12
Independent Claim 24 words
A method for inactivating lipid-containing viruses comprising exposing said viruses to an effective inactivating amount of butylated hydroxytoluene in a non-toxic pharmaceutically acceptable carrier.

References Cited (Backward Citations)

US2081284A Cited
FR1302984A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-09-20 1986-03-22 1986-09-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-09-20 1990-03-22 1990-09-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-09-20 1994-03-22 1994-09-21 $7700.00 Window Closed / Lapsed

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