US4333010A
Expired / Lapsed
US
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Dose calibrator linearity evaluation
Assignee: Individual
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Filing: 1981-05-08
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Granted: 1982-06-01
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Expires: 2001-05-08
Abstract
Abstract A method and apparatus is disclosed for evaluating the linearity of response of a radioactivity dose measurement device over a range of radioactivity dose levels. In accordance with the method, a reference dose of radiopharmaceutical in a container is placed in a central, substantially non-absorptive tube mounted atop a cylindrical spacer with a lead slug coaxial in the tube and positioned below the spacer. This assembly is placed in a measurement chamber of the measurement device, and the response of the device to the unshielded radioactivity is recorded. A succession of leaded shielding sleeves, each having a different known radioactivity attenuation capability, is placed, one at a time, over the central tube. A measurement reading of the device is recorded for indicating the response of the measurement device to the reference dose as shielded by each different sleeve. Multiplication of each response reading by a correction factor, which is a function of the attenuation capability of the sleeve used in obtaining the reading, yields data from which linearity of measurement device response can be easily calculated.
Inventors
- 👤 William H. Miller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 14:51
CPC Classifications
G; G01; G01T; G01T1/00; G01T1/02; G01D; G01D18/00
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
87 words
A test method for evaluating response of a dose calibrator for measuring the amount of radiation produced by a radioactive source subject to decay, said method comprising the steps of: (a) disposing the source for continuous measurement by the dose calibrator during the test; (b) simulating different amounts of source decay by successively differingly and incompletely shielding the source during a single test; (c) monitoring the response of the dose calibrator to the shielded source at each of the differing shieldings, and (d) comparing said monitored responses.
Claim 2
Dependent Claim
87 words
A test method for evaluating response of a dose calibrator for measuring the amount of radiation produced by a radioactive source subject to decay, said method comprising the steps of: (a) disposing the source for continuous measurement by the dose calibrator during the test; (b) simulating different amounts of source decay by successively differingly and incompletely shielding the source during a single test; (c) monitoring the response of the dose calibrator to the shielded source at each of the differing shieldings, and (d) comparing said monitored responses.
Claim 3
Dependent Claim
106 words
Apparatus for evaluating the linearity of a radiopharmaceutical dose calibrator, said apparatus comprising: (a) an assembly comprising: (i) a tubular pedestal element; (ii) a radioabsorbtive slug affixed for substantially covering a top end of the pedestal; (iii) a substantially non-radioabsorptive central tube affixed substantially atop the slug covering the pedestal end and being substantially coaxial with and having a diameter smaller than that of said pedestal, for accommodating insertion into said central tube of a reference dose of radiopharmaceutical, and (b) a plurality of radiation shielding sleeves each slidable over the central tube, each shielding sleeve having a differing and incomplete degree of radioactivity absorbing effect.
Claim 4
Dependent Claim
106 words
Apparatus for evaluating the linearity of a radiopharmaceutical dose calibrator, said apparatus comprising: (a) an assembly comprising: (i) a tubular pedestal element; (ii) a radioabsorbtive slug affixed for substantially covering a top end of the pedestal; (iii) a substantially non-radioabsorptive central tube affixed substantially atop the slug covering the pedestal end and being substantially coaxial with and having a diameter smaller than that of said pedestal, for accommodating insertion into said central tube of a reference dose of radiopharmaceutical, and (b) a plurality of radiation shielding sleeves each slidable over the central tube, each shielding sleeve having a differing and incomplete degree of radioactivity absorbing effect.
Claim 5
Dependent Claim
23 words
The apparatus of claim 2, further comprising: each sleeve having a laminate construction one layer of which being a wrap of lead foil.
Claim 6
Dependent Claim
17 words
The apparatus of claim 2, wherein the sleeves bear color coding indicating their respective radioactivity absorbing effect.
Claim 7
Dependent Claim
16 words
The apparatus of claim 2 or 4, wherein the sleeves each bear respectively unique alphanumeric indicia.
Claim 8
Dependent Claim
19 words
The apparatus of claim 2, further comprising: a spacer interposed within the central tube substantially atop the absorptive slug.
Claim 9
Dependent Claim
112 words
A test process of evaluating uniformity over time of response linearity of a radioisotope dose calibrator, said process comprising the steps of: (a) testing the dose calibrator to assure that its degree of linearity of response is initially within a predetermined standard; (b) placing a quantity of isotope in the dose calibrator for measurement; (c) shielding the radioisotope in a succession of different and incomplete degrees during a single test procedure: (d) measuring and recording the response of the dose calibrator during each of said successive shielding steps; (e) later repeating steps (c) and (d), and (f) comparing the two steps of measurements derived from the performance of steps (d) and (e).
Claim 10
Dependent Claim
112 words
A test process of evaluating uniformity over time of response linearity of a radioisotope dose calibrator, said process comprising the steps of: (a) testing the dose calibrator to assure that its degree of linearity of response is initially within a predetermined standard; (b) placing a quantity of isotope in the dose calibrator for measurement; (c) shielding the radioisotope in a succession of different and incomplete degrees during a single test procedure: (d) measuring and recording the response of the dose calibrator during each of said successive shielding steps; (e) later repeating steps (c) and (d), and (f) comparing the two steps of measurements derived from the performance of steps (d) and (e).
Claim 11
Dependent Claim
81 words
A test method for evaluating the response linearity of a radiopharmaceutical dose calibrator, said method comprising the steps of: (a) placing a referenced dose in the calibrator; (b) successively shielding the reference dose to different known and incomplete degrees during a single test procedure; (c) recording a calibrator measurement reading for each degree of shielding; (d) multiplying each reading by a factor which is a function of the degree of shielding corresponding to that reading, and (e) comparing the resulting products.
Claim 12
Dependent Claim
81 words
A test method for evaluating the response linearity of a radiopharmaceutical dose calibrator, said method comprising the steps of: (a) placing a referenced dose in the calibrator; (b) successively shielding the reference dose to different known and incomplete degrees during a single test procedure; (c) recording a calibrator measurement reading for each degree of shielding; (d) multiplying each reading by a factor which is a function of the degree of shielding corresponding to that reading, and (e) comparing the resulting products.
Claim 13
Dependent Claim
94 words
Apparatus for testing linearity of a dose calibrator comprising: (a) a central assembly comprising: (i) a central tube; (ii) a flanged plug in the bottom end of the tube; (iii) a lead annulus interposed between the flange and the tube and encircling the plug; (iv) a spacer in the central tube atop the plug, (v) a lead disc atop the spacer, and (vi) a second spacer atop the lead disc, and (b) a set of laminar shielding sleeves, for only partially shielding a source each comprising a core layer and a layer of lead.
Claim 14
Dependent Claim
94 words
Apparatus for testing linearity of a dose calibrator comprising: (a) a central assembly comprising: (i) a central tube; (ii) a flanged plug in the bottom end of the tube; (iii) a lead annulus interposed between the flange and the tube and encircling the plug; (iv) a spacer in the central tube atop the plug, (v) a lead disc atop the spacer, and (vi) a second spacer atop the lead disc, and (b) a set of laminar shielding sleeves, for only partially shielding a source each comprising a core layer and a layer of lead.
Claim 15
Dependent Claim
39 words
The apparatus of claim 9, wherein: (a) the lead of the shielding sleeves comprises a wrap of lead foil, and (b) the core layer defines a longitudinal notch in its outside surface for accommodating an edge of the foil.
Claim 16
Dependent Claim
39 words
The apparatus of claim 9, further comprising: a plastic jacket wrappable about the lead layer of each sleeve and having an edge-to-edge closure structure for adjusting the closed circumference of the jacket to fit the remainder of the sleeve.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-31 | 1985-11-30 | 1986-06-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-31 | 1989-11-30 | 1990-06-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-31 | 1993-11-30 | 1994-06-01 | $7700.00 | Window Closed / Lapsed |