US4332946A
Expired / Lapsed
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Resolution enhancing maleimide spin label for biological EPR studies
Assignee: Vanderbilt University
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Filing: 1981-04-03
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Granted: 1982-06-01
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Expires: 2001-04-03
Abstract
Abstract An improved maleimide spin label, namely, N-( 15 N-oxyl-2,2,6,6-tetra-methyl-4-piperidinyl-d 17 ) maleimide is provided for EPR spectroscopic investigations of biomedically relevant problems. Isotopic substitution of nitrogen-15 in the N--O bond and deuterium in the methyl groups (-CD 3 ) and in all positions of the piperidine ring results in simplification of the EPR spectrum, greatly improved resolution, and a marked increase in signal intensity.
Inventors
- 👤 Sindhaghatta D. Venkataramu
- 👤 Donald E. Pearson
- 👤 Albert H. Beth
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 07:24
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/04
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
18 words
As a resolution enhancing spin label for biomedical EPR applications, the compound ##STR2## N-( 15 N-oxyl-2,2,6,6-tetramethyl-4-piperidinyl-d 17 )maleimide.
Claim 2
Dependent Claim
18 words
As a resolution enhancing spin label for biomedical EPR applications, the compound ##STR2## N-( 15 N-oxyl-2,2,6,6-tetramethyl-4-piperidinyl-d 17 )maleimide.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-31 | 1985-11-30 | 1986-06-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-31 | 1989-11-30 | 1990-06-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-31 | 1993-11-30 | 1994-06-01 | $7700.00 | Window Closed / Lapsed |