US4331649A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Immune complex assay
Assignee: Murex Diagnostics Inc
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Filing: 1979-10-09
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Granted: 1982-05-25
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Expires: 1999-10-09
Abstract
Abstract Method for the estimation of immune complex and analysis of a constituent thereof. Method comprises a latex particle agglutination test in which a reagent comprising low affinity latex particles is contacted with a sample containing immune complex. The low affinity coated latex particles are latex particles coated with IgG antibodies to the complex constituent and may be prepared by contacting latex particles with the IgG antibodies, the latter optionally being substituted with a coupling agent. One or more reagents are conveniently provided in kit form.
Inventors
- 👤 Shireen M. Chantler
- 👤 William Edgar
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 12:58
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/564
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
67 words
A method for the estimation of an immune complex and analysis of a constituent thereof comprising a latex particle agglutination test in which a reagent comprising low affinity latex particles is contacted with a sample containing immune complex, the low affinity latex particles comprising latex particles coated with IgG antibodies to the complex constituent in an amount of from 2 to 10 μg per mg of latex.
Claim 2
Independent Claim
67 words
A method for the estimation of an immune complex and analysis of a constituent thereof comprising a latex particle agglutination test in which a reagent comprising low affinity latex particles is contacted with a sample containing immune complex, the low affinity latex particles comprising latex particles coated with IgG antibodies to the complex constituent in an amount of from 2 to 10 μg per mg of latex.
Claim 3
Dependent Claim
15 words
A method according to claim 1 in which the IgG antibodies are of non-human origin.
Claim 4
Dependent Claim
31 words
A method according to either claim 1 or claim 2 wherein the complex constituent is selected from the group consisting of an immunoglobulin constituent, a complement constituent or an antigen constituent.
Claim 5
Dependent Claim
15 words
A method according to claim 1 wherein the agglutination test comprises a slide agglutination test.
References Cited (Backward Citations)
US3088875A
Cited
US4118349A
Cited
GB1503547A
Cited
US4141965A
Cited
US4181636A
Cited
GB2005275B
Cited
GB2004892B
Cited
GB2027031A
Cited
GB2030293A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-24 | 1985-11-23 | 1986-05-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-24 | 1989-11-23 | 1990-05-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-24 | 1993-11-23 | 1994-05-25 | $7700.00 | Window Closed / Lapsed |