US4329339A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anthracyclinones and derivatives thereof
Assignee: Hoffmann La Roche Inc
•
Filing: 1980-05-21
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Granted: 1982-05-11
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Expires: 2000-05-21
Abstract
Abstract There is disclosed compounds of the formula <IMAGE> I wherein R1 represents a methyl or acetonyl group and R2 represents a hydrogen atom, a hydroxyl group or a group of the formula <IMAGE> +TR <IMAGE> and a process for the preparation thereof. The compounds are useful as intermediates for the preparation of anthracycline antibiotics and certain of the compounds exhibit per se activity as antibacterial and antitumor agents.
Inventors
- 👤 Akiko Fujiwara
- 👤 Tatsuo Hoshino
- 👤 Masaaki Tazoe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 00:16
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/24; C07H15/252; A; A61; A61P; A61P35/00; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C12P; C12P19/00; C12P19/44; C12P19/56; C12P29/00; C12R; C12R2001/00; C12R2001/01; C12R2001/465
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
25 words
A compound of the formula ##STR6## wherein R 1 represents a methyl or acetonyl group and R 2 represents a group of the formula ##STR7##
Claim 2
Dependent Claim
25 words
A compound of the formula ##STR6## wherein R 1 represents a methyl or acetonyl group and R 2 represents a group of the formula ##STR7##
Claim 3
Dependent Claim
15 words
The compound of claim 1 wherein R 1 is methyl and R 2 is ##STR8##
Claim 4
Dependent Claim
15 words
The compound of claim 1 wherein R 1 is acetonyl and R 2 is ##STR9##
Claim 5
Dependent Claim
15 words
The compound of claim 1 wherein R 1 is methyl and R 2 is ##STR10##
Claim 6
Dependent Claim
15 words
The compound of claim 1 wherein R 1 is acetonyl and R 2 is ##STR11##
Claim 7
Dependent Claim
40 words
A pharmaceutical composition useful in the treatment of bacterial infections which comprises as an active ingredient a compound selected from the group consisting of auramycin A, auramycin B, sulfurmycin A and sulfurmycin B in combination with a pharmaceutically compatible carrier.
Claim 8
Dependent Claim
40 words
A pharmaceutical composition useful in the treatment of bacterial infections which comprises as an active ingredient a compound selected from the group consisting of auramycin A, auramycin B, sulfurmycin A and sulfurmycin B in combination with a pharmaceutically compatible carrier.
References Cited (Backward Citations)
US3988315A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-10 | 1985-11-09 | 1986-05-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-10 | 1989-11-09 | 1990-05-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-10 | 1993-11-09 | 1994-05-11 | $7700.00 | Window Closed / Lapsed |