US4329281A
Expired / Lapsed
US
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Hapten compositions
Assignee: Roche Diabetes Care Inc
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Filing: 1979-12-21
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Granted: 1982-05-11
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Expires: 1999-12-21
Abstract
Abstract Novel hapten compositions consisting of 4-[4-[2-(aminopropyl)]phenyl]butanoic acid and its N-methyl derivative are useful in preparing immunogens which can be respectively employed in the elicitation of antibodies selective to amphetamine and methamphetamine. These antibodies can be used as reagents in immunoassays for these two compounds.
Inventors
- 👤 James G. Christenson
- 👤 Benjamin Pecherer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 11:46
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/46; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/94; G01N33/946; Y; Y10; Y10S; Y10S436/00; Y10S436/822; Y10S530/00; Y10S530/806
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
49 words
An antibody specific to amphetamine prepared by inoculating a host animal with an immunogen of the formula ##STR8## which is covalently bonded through the carboxyl group to an immunogenic carrier material, where R 1 is hydrogen and R 2 is hydrogen, and thereafter collecting serum from said host animal.
Claim 2
Dependent Claim
49 words
An antibody specific to amphetamine prepared by inoculating a host animal with an immunogen of the formula ##STR8## which is covalently bonded through the carboxyl group to an immunogenic carrier material, where R 1 is hydrogen and R 2 is hydrogen, and thereafter collecting serum from said host animal.
Claim 3
Dependent Claim
49 words
An antibody specific to methamphetamine prepared by inoculating a host animal with an immunogen of the formula ##STR9## which is covalently bonded through the carboxyl group to an immunogenic carrier material, where R 1 is methyl and R 2 is hydrogen and thereafter collecting serum from said host animal.
Claim 4
Dependent Claim
49 words
An antibody specific to methamphetamine prepared by inoculating a host animal with an immunogen of the formula ##STR9## which is covalently bonded through the carboxyl group to an immunogenic carrier material, where R 1 is methyl and R 2 is hydrogen and thereafter collecting serum from said host animal.
Claim 5
Dependent Claim
16 words
The antibody of claim 1 or 2 wherein said immunogenic carrier material is bovine serum albumen.
References Cited (Backward Citations)
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Cited
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Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-10 | 1985-11-09 | 1986-05-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-10 | 1989-11-09 | 1990-05-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-10 | 1993-11-09 | 1994-05-11 | $7700.00 | Window Closed / Lapsed |