US4328344A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Meta-amino sulfonamido-benzamides
Assignee: Shionogi and Co Ltd
•
Filing: 1980-02-26
•
Granted: 1982-05-04
•
Expires: 2000-02-26
Abstract
Abstract Meta-sulfonamido-benzamide derivatives of the formula: ##STR1## [wherein R is a hydrogen atom or a lower alkyl, cyano, or lower alkanesulfonyl group; R 1 is a lower alkyl, phenyl, amino, lower alkylamino, di(lower)alkylamino, or C 4 -C 5 alkyleneamino group; R 2 is a hydrogen or halogen atom or a lower alkyl, di(lower)alkylamino, or lower alkoxy group; R 3 is a hydrogen atom or a methyl or methoxy group; R 4 is a hydrogen or halogen atom; R 5 is a lower alkyl, lower alkenyl, C 3 -C 6 cycloalkyl, benzyl, or halogenobenzyl group; and n is 1 or zero] or their acid addition salts, showing pharmacological activity such as anti-emetic or psychotropic activity, are provided via several routes.
Inventors
- 👤 Ogata Masaru
- 👤 Hiroshi Matsumoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 16:09
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/14; C07D207/08; C07D207/09; C07D307/00; C07D307/02; C07D307/04; C07D307/10; C07D307/14
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
40 words
A compound selected from the group consisting of a compound of the formula ##STR22## wherein R 1 is amino, methylamino, t-butylamino, dimethylamino or piperidino, and R 2 is hydrogen, methyl or chlorine, and a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
40 words
A compound selected from the group consisting of a compound of the formula ##STR22## wherein R 1 is amino, methylamino, t-butylamino, dimethylamino or piperidino, and R 2 is hydrogen, methyl or chlorine, and a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-5-dimethylaminosulfonamidobenzamide.
Claim 4
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-methyl-5-dimethylaminosulfonamidobenzamide.
Claim 5
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-methyl-5-t-butylaminosulfonamidobenzamide.
Claim 6
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-methyl-5-aminosulfonamidobenzamide.
Claim 7
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-chloro-5-t-butylaminosulfonamidobenzamide.
Claim 8
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-chloro-5-aminosulfonamidobenzamide.
Claim 9
Dependent Claim
8 words
A compound according to claim 1, namely (N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-chloro-5-piperidinosulfonamidobenzamide.
Claim 10
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-5-methylaminosulfonamidobenzamide.
Claim 11
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-5-t-butylaminosulfonamidobenzamide.
Claim 12
Dependent Claim
8 words
A compound according to claim 1, namely N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-5-aminosulfonamidobenzamide.
References Cited (Backward Citations)
US3342826A
Cited
US4071351A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-03 | 1985-11-02 | 1986-05-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-03 | 1989-11-02 | 1990-05-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-03 | 1993-11-02 | 1994-05-04 | $7700.00 | Window Closed / Lapsed |