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US4318992A Expired / Lapsed US ⏱️ 0.0 years remaining

Fermenter

Assignee: Instituto Nacional de Higiene Rafael Rangel
•
Filing: 1980-05-30
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Granted: 1982-03-09
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Expires: 2000-05-30
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Abstract

Abstract A fermenter, suitable for use in the production of biological materials is, constituted by a fermenter container, connected a seeder, a sampler, a harvester and a gas-decontaminating and venting system for gases produced within the apparatus. The fermenter container can also be provided with a heater, as well as a magnetic shaker and a support therefor.

Inventors

  • 👤 Yolanda M. Mila-de-la-Roca
  • 👤 Beltran V. Azuaje
  • 👤 Omar R. Gil

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 11:04
CPC Classifications
C; C12; C12M; C12M23/00; C12M23/02; C12M23/08; C12M23/38

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 289 words
A fermentation apparatus comprising: a fermentation container formed with a closure at the top thereof and adapted to receive a culture medium; a first tube extending through said closure into said container and terminating at an upper portion of said container while being connected to a condenser coil for condensing water vapor formed in said container and returning the condensed water vapor thereto; a decontamination and venting system connected to said coil and including a vessel containing a caustic solution and at least one further vessel disposed between the caustic solution vessel having tubes opening into the top thereof and respectively communicating with said coil and with said caustic solution vessel below the level of the caustic solution therein; temperature monitoring means extending through said closure into said vessel; a second tube extending through said closure into said vessel, provided with an air filter and connectable to a source of fluid pressure operable to draw material into said container or drive material from said container; a third tube extending through said closure into said container and extending substantially to the bottom thereof; a harvesting system including a pair of vessels connected to said third tube for receiving material displaced by fluid pressure through said third tube; a fourth tube extending through said closure into said container substantially to the bottom thereof and connected to a sampling vessel; and a fifth tube extending through said closure substantially to the bottom of said container and connected to a seeding vessel adapted to receive an inoculum for said medium and enable said inoculum to be transferred to said container through said fifth tube, said harvesting, sampling and seeding vessels each being provided with air filters adapted to be connected to said source.
Claim 2
Dependent Claim 289 words
A fermentation apparatus comprising: a fermentation container formed with a closure at the top thereof and adapted to receive a culture medium; a first tube extending through said closure into said container and terminating at an upper portion of said container while being connected to a condenser coil for condensing water vapor formed in said container and returning the condensed water vapor thereto; a decontamination and venting system connected to said coil and including a vessel containing a caustic solution and at least one further vessel disposed between the caustic solution vessel having tubes opening into the top thereof and respectively communicating with said coil and with said caustic solution vessel below the level of the caustic solution therein; temperature monitoring means extending through said closure into said vessel; a second tube extending through said closure into said vessel, provided with an air filter and connectable to a source of fluid pressure operable to draw material into said container or drive material from said container; a third tube extending through said closure into said container and extending substantially to the bottom thereof; a harvesting system including a pair of vessels connected to said third tube for receiving material displaced by fluid pressure through said third tube; a fourth tube extending through said closure into said container substantially to the bottom thereof and connected to a sampling vessel; and a fifth tube extending through said closure substantially to the bottom of said container and connected to a seeding vessel adapted to receive an inoculum for said medium and enable said inoculum to be transferred to said container through said fifth tube, said harvesting, sampling and seeding vessels each being provided with air filters adapted to be connected to said source.
Claim 3
Dependent Claim 54 words
The apparatus defined in claim 1 wherein said decontamination and venting system comprises a further vessel having a side opening connected to said coil, a tube connected through an air filter between the top of the latter vessel and said further vessel of said system, said caustic solution vessel being vented to the atmosphere.
Claim 4
Dependent Claim 15 words
The apparatus defined in claim 2 wherein said seeding and sampling vessels are assay tubes.

References Cited (Backward Citations)

US1244995A Cited
US2672053A Cited
US3172235A Cited
US3219319A Cited
US3607737A Cited
US3715298A Cited
US3926738A Cited
US4116778A Cited
US4167450A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-03-08 1985-09-07 1986-03-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-03-08 1989-09-07 1990-03-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-03-08 1993-09-07 1994-03-09 $7700.00 Window Closed / Lapsed

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