US4318907A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for treating acne vulgaris and compositions useful for that purpose
Assignee: Westwood Pharmaceuticals Inc
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Filing: 1978-04-04
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Granted: 1982-03-09
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Expires: 1998-04-04
Abstract
Abstract Procedure for treating acne vulgaris that uses salicylic acid and benzoyl peroxide either sequentially or simultaneously. Compositions for practicing each of these aspects of the invention are also described.
Inventors
- 👤 Albert M. Kligman
- 👤 Walter L. McKenzie
- 👤 Peter F. Ciesla
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 07:49
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/38; A61K8/36; A61K8/368; A61Q; A61Q19/00
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
105 words
A method for treating acne vulgaris comprising applying to the skin of a subject having this condition a therapeutically effective of salicylic acid and benzoyl peroxide for a period of time sufficient to alleviate symptoms of said acne condition, said salicylic acid being applied at a concentration in the range of from about 3% to 7% by weight and said benzoyl peroxide being applied at a concentration of about 3% to 20% by weight; said percentages being expressed on a weight basis based on the total weight of compositions containing said benzoyl peroxide or salicylic acid or the combination of benzoyl peroxide and salicylic acid.
Claim 2
Independent Claim
105 words
A method for treating acne vulgaris comprising applying to the skin of a subject having this condition a therapeutically effective of salicylic acid and benzoyl peroxide for a period of time sufficient to alleviate symptoms of said acne condition, said salicylic acid being applied at a concentration in the range of from about 3% to 7% by weight and said benzoyl peroxide being applied at a concentration of about 3% to 20% by weight; said percentages being expressed on a weight basis based on the total weight of compositions containing said benzoyl peroxide or salicylic acid or the combination of benzoyl peroxide and salicylic acid.
Claim 3
Dependent Claim
31 words
A method according to claim 1 in which the concentration of the salicylic acid is about 5% by weight and the concentration of the benzoyl peroxide is about 5% by weight.
Claim 4
Dependent Claim
17 words
A method according to claim 2 in which the salicylic acid and benzoyl peroxide are applied sequentially.
Claim 5
Dependent Claim
17 words
A method according to claim 2 in which said salicylic acid and benzoyl peroxide are applied simultaneously.
Claim 6
Dependent Claim
23 words
A method according to claim 4 in which said salicylic acid and said benzoyl peroxide are contained in the same pharmaceutically accpetable vehicle.
Claim 7
Dependent Claim
35 words
A topical therapeutic composition comprising a pharmaceutically acceptable vehicle containing by weight, based on the total weight of said composition, from about 3% to about 7% salicylic acid and about 3% to 20% benzoyl peroxide.
Claim 8
Dependent Claim
35 words
A topical therapeutic composition comprising a pharmaceutically acceptable vehicle containing by weight, based on the total weight of said composition, from about 3% to about 7% salicylic acid and about 3% to 20% benzoyl peroxide.
Claim 9
Dependent Claim
15 words
A composition according to claim 6 containing about 5% salicylic acid and 5% benzoyl peroxide.
Claim 10
Dependent Claim
14 words
A composition according to claim 7 in which said vehicle is an aqueous gel.
Claim 11
Dependent Claim
18 words
A composition according to claim 8 containing as gelling and/or thickening agents magnesium aluminum silicate and hydroxypropyl methylcellulose.
Claim 12
Dependent Claim
83 words
A composition according to claim 9 in which the magnesium aluminum silicate is present in an amount in the range of from about 0.5 to about 3.0% by weight based on the total weight of the composition and said hydroxypropyl methylcellulose is present in an amount in the range of from about 0.5 to 2.5% by weight based on the total weight of the composition; the combined amount of said magnesium aluminum silicate and said hydroxypropyl methylcellulose not exceeding about 5% by weight.
Claim 13
Dependent Claim
23 words
A composition according to claim 10 containing about 2% by weight of magnesium aluminum silicate and about 1.25% by weight of hydroxypropyl methylcellulose.
Claim 14
Dependent Claim
29 words
A composition, according to claim 10, further including an amount of a metal sequestering or chelating agent sufficient to prevent product discoloration due to salicylic acid and metals interaction.
Claim 15
Dependent Claim
30 words
A composition, according to claim 12 further including from about 0.5% to 2.0% by weight, based on the total weight of the composition, of a water soluble Cold Process Starch.
References Cited (Backward Citations)
US2095571A
Cited
US2523867A
Cited
US2614962A
Cited
GB964444A
Cited
BE645930A
Cited
US3343540A
Cited
US3265571A
Cited
GB1185685A
Cited
US3530217A
Cited
US3535422A
Cited
US3821370A
Cited
US3949072A
Cited
DE2340568A1
Cited
DE2416542A1
Cited
US3987202A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-03-08 | 1985-09-07 | 1986-03-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-03-08 | 1989-09-07 | 1990-03-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-03-08 | 1993-09-07 | 1994-03-09 | $7700.00 | Window Closed / Lapsed |