US4316888A
Expired / Lapsed
US
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Method and composition of reducing pain
Assignee: Whitby Research Inc
•
Filing: 1980-04-15
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Granted: 1982-02-23
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Expires: 2000-04-15
Abstract
Abstract A method for temporarily reducing pain in animals including humans, and especially pain associated with gastrointestinal dysfunction, by administering to an animal having pain an effective, pain reducing amount of dextromethorphan, preferably as the hydrobromide.
Inventors
- 👤 Eric L. Nelson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 15:38
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/06; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/485; A61P; A61P25/00; A61P25/04
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
36 words
A method of temporarily reducing pain associated with gastrointestinal dysfunction in humans comprising administering to a human having pain associated with gastrointestinal dysfunction an effective, pain reducing amount of dextromethorphan or a pharmaceutically acceptable salt thereof.
Claim 2
Independent Claim
36 words
A method of temporarily reducing pain associated with gastrointestinal dysfunction in humans comprising administering to a human having pain associated with gastrointestinal dysfunction an effective, pain reducing amount of dextromethorphan or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
23 words
The method of claim 1 wherein the dextromethorphan is administered in a daily dosage regimen of about 1 mg to about 200 mg.
Claim 4
Dependent Claim
23 words
The method of claim 1 wherein the dextromethorphan is administered in a daily dosage regimen of about 10 mg to about 100 mg.
Claim 5
Dependent Claim
17 words
The method of claim 1 wherein the dextromethorphan is administered in the form of its hydrobromide salt.
Claim 6
Dependent Claim
12 words
The method of claim 4 wherein the dextromethorphan hydrobromide is administered orally.
Claim 7
Dependent Claim
29 words
The method of claim 1 wherein the dextromethorphan is administered in an oral dosage form selected from the group consisting of a tablet, capsule, lozenge, syrup, suspension and elixir.
Claim 8
Dependent Claim
21 words
The method of claim 6 wherein the oral dosage form additionally comprises an effective, gastric acid neutralizing amount of an antacid.
Claim 9
Dependent Claim
20 words
The method of claim 6 wherein the oral dosage form additionally comprises an effective gas inhibiting amount of an antiflatulent.
Claim 10
Dependent Claim
10 words
The method of claim 8 wherein the antiflatulent is simethicone.
Claim 11
Dependent Claim
30 words
The method of claim 6 wherein the oral dosage form additionally comprises an effective, gastric acid neutralizing amount of an antacid and an effective, gas inhibiting amount of an antiflatulent.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-02-22 | 1985-08-24 | 1986-02-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-02-22 | 1989-08-24 | 1990-02-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-02-22 | 1993-08-24 | 1994-02-23 | $7700.00 | Window Closed / Lapsed |