US4315002A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Solid pharmaceutical or diagnostic agent containing dextran and its preparation
Assignee: BASF SE
•
Filing: 1980-05-30
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Granted: 1982-02-09
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Expires: 2000-05-30
Abstract
Abstract A process for the preparation of a solid pharmaceutical or diagnostic composition in which the active substance and dextran are dissolved in water, the solution is placed in a mold and is thereafter lyophilized to form a solid abrasion-resistant tablet which can further be compressed to reduce its rate of disintegration in water. The invention is also directed to the pharmaceutical or diagnostic agent produced by this process.
Inventors
- 👤 Robert Maurer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 07:54
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/19; A61K47/00; A61K47/30; A61K47/36; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
49 words
A process for the preparation of a solid composition containing a pharmaceutical or diagnostic agent which comprises: dissolving the pharmaceutical or diagnostic agent and dextran in water, placing the solution in a mold, and thereafter lyophilizing the solution to form a solid abrasion-resistant tablet of said agent and dextran.
Claim 2
Dependent Claim
49 words
A process for the preparation of a solid composition containing a pharmaceutical or diagnostic agent which comprises: dissolving the pharmaceutical or diagnostic agent and dextran in water, placing the solution in a mold, and thereafter lyophilizing the solution to form a solid abrasion-resistant tablet of said agent and dextran.
Claim 3
Dependent Claim
20 words
The process of claim 1, wherein the solid abrasion-resistant tablet is compressed to reduce its rate of disintegration in water.
Claim 4
Dependent Claim
16 words
The process of claim 1 or 2, wherein the agent is an enzyme or an antibiotic.
Claim 5
Dependent Claim
26 words
The process of claim 1 or 2, wherein the agent is selected from the group consisting of pencillins, streptomycins, tetracyclins, fibrinogenase, aminoacid-oxidase, streptokinase, urokinase and caseinase.
Claim 6
Dependent Claim
9 words
The composition produced by the process of claim 1.
Claim 7
Dependent Claim
9 words
The composition produced by the process of claim 2.
Claim 8
Dependent Claim
30 words
The composition produced by the process of claim 4, wherein the agent is present in an amount from 10 to 50% by weight based on the weight of the composition.
References Cited (Backward Citations)
US3655838A
Cited
US4134943A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-02-08 | 1985-08-10 | 1986-02-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-02-08 | 1989-08-10 | 1990-02-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-02-08 | 1993-08-10 | 1994-02-09 | $7700.00 | Window Closed / Lapsed |