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US4312835A Expired / Lapsed US ⏱️ 0.0 years remaining

Thermal control means for liquid chromatograph samples

Assignee: Wyeth Holdings LLC
•
Filing: 1980-04-21
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Granted: 1982-01-26
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Expires: 2000-04-21
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Abstract

Abstract A Peltier effect thermal control sample containment means for an automatic sample holding apparatus used in conjunction with a liquid chromatograph analysis. The apparatus provides for the cooling or heating of a plurality of liquid chromatography samples and the maintenance of said samples at specific temperatures for extended periods of time.

Inventors

  • 👤 Bart J. Zoltan
  • 👤 Richard A. Leese

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 08:20
CPC Classifications
F; F25; F25B; F25B21/00; F25B21/02; G; G01; G01N; G01N30/00; G01N30/02; G01N30/04; G01N30/06; G01N30/26; G01N30/28; G01N30/30; G01N2030/303

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 125 words
In a liquid chromatographic sampling device having an automatic sample injector, the improvement comprising a thermal control sample containment means comprising: (a) sample holder body of a heat conductive material having from one to a plurality of sample contaimment means and from one to a plurality of (b) Peltier devices, said devices each having an active surface and a reactive surface and said sample holder body being in intimate contact with the active surface of each Peltier device adapted to provide cooling or heating of the samples being chromatographed and (c) insulation between said sample holder body and said reactive surface of each Peltier device and each said reactive surface of each said Peltier device being in intimate contact with (d) a heat exchange means.
Claim 2
Dependent Claim 125 words
In a liquid chromatographic sampling device having an automatic sample injector, the improvement comprising a thermal control sample containment means comprising: (a) sample holder body of a heat conductive material having from one to a plurality of sample contaimment means and from one to a plurality of (b) Peltier devices, said devices each having an active surface and a reactive surface and said sample holder body being in intimate contact with the active surface of each Peltier device adapted to provide cooling or heating of the samples being chromatographed and (c) insulation between said sample holder body and said reactive surface of each Peltier device and each said reactive surface of each said Peltier device being in intimate contact with (d) a heat exchange means.
Claim 3
Dependent Claim 136 words
In a liquid chromatography sampling device having an automatic sample injector, the improvement comprising a thermal control sample containment means capable of reducing sample temperature from about 20°-25° C. to about 0°-4° C. comprising: (a) sample holder body of a heat conductive material having from one to a plurality of sample containment means and from one to a plurality of (b) Peltier devices, said devices each having an active surface and a reactive surface and said sample holder body being in intimate contact with the active surface of each Peltier device adapted to provide cooling of the samples being chromatographed and (c) insulation between said sample holder body and said reactive surface of each Peltier device and each said reactive surface of each said Peltier device being in intimate contact with (d) a heat exchange means.
Claim 4
Dependent Claim 136 words
In a liquid chromatography sampling device having an automatic sample injector, the improvement comprising a thermal control sample containment means capable of reducing sample temperature from about 20°-25° C. to about 0°-4° C. comprising: (a) sample holder body of a heat conductive material having from one to a plurality of sample containment means and from one to a plurality of (b) Peltier devices, said devices each having an active surface and a reactive surface and said sample holder body being in intimate contact with the active surface of each Peltier device adapted to provide cooling of the samples being chromatographed and (c) insulation between said sample holder body and said reactive surface of each Peltier device and each said reactive surface of each said Peltier device being in intimate contact with (d) a heat exchange means.

References Cited (Backward Citations)

US3271112A Cited
US3607099A Cited
US3932067A Cited
US3975946A Cited
US3918913A Cited
US4059009A Cited
US4131547A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-01-25 1985-07-27 1986-01-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-01-25 1989-07-27 1990-01-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-01-25 1993-07-27 1994-01-26 $7700.00 Window Closed / Lapsed

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