Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids

Claim 1

A compound having the formula ##STR7## wherein R 1 and R 2 are the same or different and are hydrogen, alkyl, cycloalkyl, 1-adamantyl, aryl, arylalkyl, alkylcarbonyl, arylcarbonyl, arylalkylcarbonyl, alkylsulfonyl, arylsulfonyl, or arylvinylcarbonyl; R 3 is hydrogen, alkyl, aryl, arylalkyl, alkanoyl or arylcarbonyl; R 4 is hydrogen, alkyl, alkylthio, or trifluoromethyl; R 5 is hydrogen, alkyl, or arylalkyl; n is 0, 1 or 2; and p is 1 or 2; or a salt thereof, or symmetrical dimer thereof; wherein the term "aryl" refers to phenyl, 1-naphthyl, 2-naphthyl or phenyl substituted with halogen, alkyl, alkoxy, alkylthio, hydroxy, alkanoyl, nitro, amino, dialkylamino, phenyl or trifluoromethyl groups; the term "cycloalkyl" refers to groups having 3 to 7 carbon atoms; the term "alkanoyl" refers to groups having up to 9 carbon atoms; and the terms "alkyl" and "alkoxy" refer to groups having 1 to 8 carbon atoms.