US4307077A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sulfonated bis(naphthoxy)alkanes as dental plaque barriers
Assignee: Johnson and Johnson Hospital Services Inc
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Filing: 1980-07-25
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Granted: 1981-12-22
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Expires: 2000-07-25
Abstract
Abstract Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated bis(naphthoxy)alkanes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.
Inventors
- 👤 Carl J. Buck
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 22:35
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/46; A61K8/466; C; C07; C07C; C07C309/00; C07C43/00; C07C43/02; C07C43/20; C07C43/202
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
105 words
A sulfonated alpha, omega-bis(naphthoxy)alkane having a structure selected from the group consisting of structure (A), ##STR6## and structure (B), ##STR7## and structure (C), ##STR8## wherein R is hydrogen or a linear or branched alkyl having from 1 to 20 carbon atoms, n is an integer from 2 to 12, and M is selected from the group consisting of hydrogen, lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, ammonium and the substituted ammonium ions derived from pharmaceutically acceptable organic amines; provided that R and n are so selected that the weight percent of (SO 3 M) the groups is in the range of about 18% to 35%.
Claim 2
Dependent Claim
105 words
A sulfonated alpha, omega-bis(naphthoxy)alkane having a structure selected from the group consisting of structure (A), ##STR6## and structure (B), ##STR7## and structure (C), ##STR8## wherein R is hydrogen or a linear or branched alkyl having from 1 to 20 carbon atoms, n is an integer from 2 to 12, and M is selected from the group consisting of hydrogen, lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, ammonium and the substituted ammonium ions derived from pharmaceutically acceptable organic amines; provided that R and n are so selected that the weight percent of (SO 3 M) the groups is in the range of about 18% to 35%.
Claim 3
Dependent Claim
137 words
An oral hygiene composition comprising an effective amount for preventing attachment of dental plaque to teeth of a sulfonated alpha, omega-bis(naphthoxy)alkane having a structure selected from the group consisting of structure (A), ##STR9## and structure (B), ##STR10## and structure (C), ##STR11## wherein R is hydrogen or a linear or branched alkyl having from 1 to 20 carbon atoms, n is an integer from 2 to 12, and M is selected from the group consisting of lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, hydrogen, ammonium, and substituted ammonium ions derived from pharmaceutically acceptable organic amines, provided further that R and n are so selected that the weight percent of the SO 3 M groups is between about 18 and about 35, in a pharmaceutically acceptable oral hygiene vehicle compatible with said compound of structure (A), (B) or (C).
Claim 4
Dependent Claim
137 words
An oral hygiene composition comprising an effective amount for preventing attachment of dental plaque to teeth of a sulfonated alpha, omega-bis(naphthoxy)alkane having a structure selected from the group consisting of structure (A), ##STR9## and structure (B), ##STR10## and structure (C), ##STR11## wherein R is hydrogen or a linear or branched alkyl having from 1 to 20 carbon atoms, n is an integer from 2 to 12, and M is selected from the group consisting of lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, hydrogen, ammonium, and substituted ammonium ions derived from pharmaceutically acceptable organic amines, provided further that R and n are so selected that the weight percent of the SO 3 M groups is between about 18 and about 35, in a pharmaceutically acceptable oral hygiene vehicle compatible with said compound of structure (A), (B) or (C).
Claim 5
Dependent Claim
24 words
The composition of claim 2 wherein M is a metal selected from the group consisting of potassium, lithium, sodium, calcium, magnesium, zinc and aluminum.
Claim 6
Dependent Claim
21 words
A method of preventing attachment of dental plaque to teeth comprising periodically applying to the teeth a composition of claim 2.
Claim 7
Dependent Claim
19 words
The method of claim 4 wherein said composition is applied from about 1 to about 3 times per day.
References Cited (Backward Citations)
US3812178A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1984-12-21 | 1985-06-22 | 1985-12-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-12-21 | 1989-06-22 | 1989-12-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-12-21 | 1993-06-22 | 1993-12-22 | $7700.00 | Window Closed / Lapsed |